Results 201 to 210 of about 447,624 (394)

Genomes, expression profiles, and diversity of mitochondria of the White-footed Deermouse Peromyscus leucopus, reservoir of Lyme disease and other zoonoses. [PDF]

open access: yes, 2019
The cricetine rodents Peromyscus leucopus and P. maniculatus are key reservoirs for several zoonotic diseases in North America. We determined the complete circular mitochondrial genome sequences of representatives of 3 different stock colonies of P ...
Baldwin-Brown, James   +5 more
core   +1 more source

The complete mitochondrial genomes of Pangasius nasutus and P. conchophilus (Siluriformes: Pangasiidae)

open access: diamond, 2023
Siti Amalia Aisyah Abdul Halim   +4 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

open access: yesAdvanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen   +31 more
wiley   +1 more source

The complete mitochondrial genome of Halichoeres margaritaceus (Actinopterygii, Labridae)

open access: yesMitochondrial DNA. Part B. Resources
Halichoeres margaritaceus Valenciennes 1839 is a polygynous species of coral fish. We sequenced the complete mitochondrial genome of H. margaritaceus, and conducted a comprehensive analysis to reveal its characteristics.
Xin Huang   +7 more
doaj   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong   +21 more
wiley   +1 more source

Tie2‐Dependent Mechanisms Influence Leptomeningeal Collateral Dynamics and Reperfusion Following Stroke

open access: yesAdvanced Science, EarlyView.
This work demonstrates that endothelial EphA4 limits Tie2 activation and curbs leptomeningeal collateral expansion after ischemic stroke. Pharmacological activation of Tie2 by an Ang‐1 mimetic or genetic loss of EphA4 stimulates collateral vessel growth, improves cerebral perfusion, and enhances neurological recovery.
Alexandra M. Kaloss   +9 more
wiley   +1 more source

The complete mitochondrial genome ofYuukianura szeptyckiiDeharveng & Weiner 1984 (Collembola: Neanuridae) [PDF]

open access: diamond, 2021
June Wee   +6 more
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Characterization of the complete mitochondrial genome sequence of Jialuo sheep (Ovis aries) [PDF]

open access: diamond, 2019
Donghai Fu   +11 more
openalex   +1 more source

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