Results 41 to 50 of about 1,456,287 (196)

Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer [PDF]

, 2013
Background : Preoperative radiotherapy (RT) decreases local recurrence rate and improves survival in stage II and III rectal cancer patients. The combination of chemotherapy with RT has a sound radiobiological rationale, and phase II trials of combined ...
Ceelen, Wim, DE CALUWE, LAURA, Van Nieuwenhove, Yves   +2 more
core   +1 more source

Pathological complete response in pancreatic adenocarcinoma with FOLFIRINOX

BMJ Case Reports, 2018
The report describes a patient who presented to our centre with abdominal pain and significant weight loss due to adenocarcinoma of the tail of the pancreas. The cancer was deemed as ‘resectable disease associated with morbid surgical outcomes’ due to the local involvement of the vessels and adjacent organs.
Chien-Ting Kao, Muhammad Aziz, Anup Kasi
openaire   +3 more sources

Impact of remnant vital tissue after locoregional treatment and liver transplant in hepatocellular cancer patients. A multicentre cohort study [PDF]

, 2018
The role of pathological findings after locoregional treatments as predictors of hepatocellular cancer recurrence after liver transplantation has been poorly addressed.
Angelico, Mario, Angelico, Roberta, Carvalheiro, Amanda, Iesari, Samuele, Komuta, Mina, Lai, Quirino, Lerut, Jan, Manzia, Tommaso M., Montalti, Roberto, Nicolini, Daniele, Orlacchio, Antonio, Palmieri, Giampiero, Perera, M. Thamara P. R., Quaranta, Claudia, Scarpelli, Marina, Shah, Tahir, Tisone, Giuseppe, Vivarelli, Marco   +17 more
core   +1 more source

Neoadjuvant durvalumab improves survival in early triple-negative breast cancer independent of pathological complete response.

Annals of Oncology, 2022
BACKGROUND Addition of immune checkpoint inhibitors (CPI) to neoadjuvant chemotherapy (NACT) is a promising strategy in early breast cancer, but the optimal duration of therapy is currently unknown.
S. Loibl, A. Schneeweiss, J. Huober, M. Braun, J. Rey, J. Blohmer, J. Furlanetto, D. Zahm, C. Hanusch, J. Thomalla, C. Jackisch, P. Staib, T. Link, K. Rhiem, C. Solbach, P. Fasching, V. Nekljudova, C. Denkert, M. Untch   +18 more
semanticscholar   +1 more source

Novel schedule for treatment of inflammatory breast cancer [PDF]

, 2016
Inflammatory breast cancer (IBC) is the most aggressive form of this tumor, with the clinical and biological characteristics of a rapidly proliferating disease.
Cefalì, K, Corvino, R, D'Aniello, D, De Iuliis, F, Lanza, R, Scarpa, Susanna   +5 more
core  

Radiomics Model Based on Non-Contrast CT Shows No Predictive Power for Complete Pathological Response in Locally Advanced Rectal Cancer

Cancers, 2019
(1) Background: About 15% of the patients undergoing neoadjuvant chemoradiation for locally advanced rectal cancer exhibit pathological complete response (pCR).
Gordian Hamerla, H. Meyer, P. Hambsch, U. Wolf, T. Kuhnt, K. Hoffmann, A. Surov   +6 more
semanticscholar   +1 more source

Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre observational study.

The Lancet Digital Health, 2022
BACKGROUND Accurate prediction of tumour response to neoadjuvant chemoradiotherapy enables personalised perioperative therapy for locally advanced rectal cancer.
Li-Li Feng, Zhenyu Liu, Chao Li, Zhenhui Li, X. Lou, Lizhi Shao, Yunlong Wang, Yan-Qiang Huang, Haiyang Chen, X. Pang, Shuai Liu, F. He, Jian Zheng, Xiaochun Meng, P. Xie, Guanyu Yang, Yi Ding, M. Wei, Jingping Yun, M. Hung, Weihua Zhou, D. Wahl, P. Lan, Jie Tian, Xiang-bo Wan   +24 more
semanticscholar   +1 more source

Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer [PDF]

, 2013
Background: Preoperative radiochemotherapy (RCT) with 5-FU or capecitabine is the standard of care for patients with locally advanced rectal cancer (LARC). Preoperative RCT achieves pathological complete response rates (pCR) of 10-15%.
Arnold, Dirk, Dellas, Kathrin, Dunst, Jürgen, Engel, Erik, Höhler, Thomas, Reese, Thomas, Richter, Michael, Rödel, Claus, Wagner, Wolfgang, Würschmidt, Florian   +9 more
core   +1 more source

Magnetic Resonance Texture Analysis in Identifying Complete Pathological Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer

Diseases of the Colon & Rectum, 2019
BACKGROUND: A certain proportion of patients with locally advanced rectal cancer experience complete response after undergoing neoadjuvant chemoradiotherapy.
M. Aker, B. Ganeshan, A. Afaq, S. Wan, A. Groves, T. Arulampalam   +5 more
semanticscholar   +1 more source

Complete Pathological Response Following Radiochemotherapy for Locally Advanced Rectal Cancer: Short and Long-term Outcome

Anticancer Research, 2019
Background/Aim: Preoperative radiochemotherapy (RCT) followed by total mesorectum excision has become the gold standard for locally advanced carcinoma of the low and middle rectum.
Othman Iskander, L. Courtot, N. Tabchouri, A. Artus, N. Michot, Olivier Muller, Urs Pabst-Giger, P. Bourlier, Aurore Kraemer-Bucur, T. Lecomte, S. Guyétant, S. Chapet, G. Calais, É. Salame, M. Ouaïssi   +14 more
semanticscholar   +1 more source