Results 211 to 220 of about 9,924,949 (260)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Cardiac Biomarker Complete Response in AL Amyloidosis: Characteristics, Cardiac Recovery, and Survival of 63 Patients. [PDF]

JACC CardioOncol
Muchtar E, Geyer S, Dispenzieri A, Grogan M, Kourelis TV, Buadi FK, Kapoor P, Dingli D, Gonsalves W, Leung N, Merlini G, Rosenthal J, Boilson B, Lyle M, Frantz JG, Hayman SR, Lacy MQ, Siddiqui M, Cook J, Abdallah N, Binder M, Zanwar S, Lin Y, Warsame R, Kyle RA, Rajkumar SV, Kumar SK, Gertz MA.   +27 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Complete Issue

, 2020
Issue, Complete
core   +1 more source

Adjuvant therapy after pathological complete response in patients with non-small cell lung cancer: a multicenter retrospective cohort study. [PDF]

Transl Lung Cancer Res
Cui Y, Zhang X, Wang M, Liu G, Liu C, Sun L, Zhang Z, Wang S, Xie J, Zhang Z, Wang C, Zhang B, Hu M, Zheng K, Wang H, Li H, Yue D.   +16 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Radiomics analysis of restaging MRI for detection of pathological complete response in locally advanced rectal cancer. [PDF]

Eur J Radiol Open
Ambrosini I, Francischello R, Fanni SC, Faggioni L, Aringhieri G, Fruzza R, Cwiklinska K, Caputo FP, Aghakhanyan G, Neri E, Lencioni R, Cioni D.   +11 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Correction: Case Report: Complete response and prolonged survival to alectinib in a NSCLC patient with metastases harboring a rare WDR43::ALK structural deletion. [PDF]

Front Oncol
Frontiers Production Office.
europepmc   +1 more source