Results 21 to 30 of about 9,924,949 (260)

Durable Complete Response to Pembrolizumab in Esophageal Squamous Cell Carcinoma With Divergent Microsatellite Status: A Case Report

Frontiers in Oncology, 2021
Microsatellite instability-high (MSI-H) is widely believed to be a biomarker for immune checkpoint inhibitors (ICIs) such as pembrolizumab in solid tumors.
Tian Zeng, Lei Zhang, Can Chen, Xiang Zhao, Xiaoqing Liu, Fengwei Ran, Tingting Yong, Ying Yang, Henghui Zhang, Henghui Zhang, Henghui Zhang, Yanling Zhang   +11 more
doaj   +1 more source

Complete response to third-line treatment with trifluridine/tipiracil (TAS-102) in stage IV colon adenocarcinoma

Exploration of Targeted Anti-tumor Therapy, 2023
A clinical case of a 61-year-old female diagnosed with stage IV right colon adenocarcinoma (unresectable liver and multiple lymph node metastases at the time of diagnosis), Kirsten rat sarcoma viral oncogene homolog (KRAS), neuroblastoma rat sarcoma ...
Celia Lara-Morga, Magda Palka-Kotlowska, Sara Custodio-Cabello, Vilma Pacheco-Barcia, Luis Cabezón-Gutiérrez   +4 more
doaj   +1 more source

Immune surveillance activation after neoadjuvant therapy for esophageal adenocarcinoma and complete response

OncoImmunology, 2020
After neoadjuvant chemoradiotherapy for esophageal adenocarcinoma, up to 29% of patients have a pathological complete response (pCR). What to do afterward is still under debate.
Andromachi Kotsafti, Melania Scarpa, Francesco Cavallin, Matteo Fassan, Roberta Salmaso, Andrea Porzionato, Luca Saadeh, Matteo Cagol, Rita Alfieri, Carlo Castoro, Massimo Rugge, Ignazio Castagliuolo, Marco Scarpa   +12 more
doaj   +1 more source

A prospective randomized comparison of concurrent chemoradiation with neoadjuvant and adjuvant chemotherapy with concurrent chemoradiation alone for locally advanced carcinoma cervix

Indian Journal of Medical and Paediatric Oncology, 2019
Aims: The aim of this study was to compare concurrent chemoradiation along with neoadjuvant and adjuvant chemotherapy versus concurrent chemoradiation alone in locally advanced cervical cancer regarding treatment response and toxicities.
Rahul Singh, M LB Bhatt, Rajendra Kumar, Kirti Srivastava, R K Grover, Pragya Shukla, Vijay P Raturi, Roopali, Jalaj Gaur, Mandira Saha, Dewesh Kishan   +10 more
doaj   +1 more source

Predictive Factors for Complete Response and Recurrence after Transarterial Chemoembolization in Hepatocellular Carcinoma

Gut and Liver, 2017
Background/AimsTo investigate the predictive factors for complete response (CR) and recurrence after CR in patients with hepatocellular carcinoma (HCC) treated with transarterial chemoembolization (TACE).Methods : Among 691 newly diagnosed HCC patients ...
Shin Ok Jeong, Eui Bae Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyune Kim, Sang Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim, Yong Jae Kim, Dong Erk Goo, Su Yeon Park   +13 more
doaj   +1 more source

The effect of tislelizumab on complete and pathological complete response in non-small cell lung cancer: a systematic review and meta-analysis

Frontiers in Oncology
BackgroundImmune checkpoint inhibitors have transformed non-small cell lung cancer (NSCLC) treatment, and while overall survival (OS) and progression-free survival (PFS) are well-established, a comprehensive meta-analysis focusing on complete response ...
Qian Feng, Xiaoxia Yan, Liping Gao, Hui Li, Baik Sarah, Russo Anna, Hongying Jiang   +6 more
doaj   +1 more source

Minimal residual disease detection by next-generation sequencing in multiple myeloma: Promise and challenges for response-adapted therapy

Frontiers in Oncology, 2022
Assessment of minimal residual disease (MRD) is becoming a standard diagnostic tool for curable hematological malignancies such as chronic and acute myeloid leukemia. Multiple myeloma (MM) remains an incurable disease, as a major portion of patients even
Valeria Ferla, Elena Antonini, Tommaso Perini, Tommaso Perini, Francesca Farina, Serena Masottini, Simona Malato, Sarah Marktel, Maria Teresa Lupo Stanghellini, Cristina Tresoldi, Fabio Ciceri, Fabio Ciceri, Magda Marcatti   +12 more
doaj   +1 more source

Microsatellite instability and its associations with the clinicopathologic characteristics of diffuse large B‐cell lymphoma

Cancer Medicine, 2020
Microsatellite instability (MSI) has been investigated as a prognostic and predictive factor for chemotherapy in colorectal cancer and has recently been demonstrated to be predictive of the PD‐1/PD‐L1 checkpoint blockade response in various solid tumors.
Tian Tian, Jiwei Li, Tian Xue, Baohua Yu, Xiaoqiu Li, Xiaoyan Zhou   +5 more
doaj   +1 more source

the ultimate in pleasurable reading [PDF]

, 1989
This is the Climax magazine of September 13, 1989, Vol. 2, No. 7.• Maryam and her baby. • Adan's dream girl. • Me, to be Nigeria’s president? No. way – By Mary Onyali, African Queen of tracks. • Holyland where miracles are performed.
COMPLETE Communications limited
core   +8 more sources

Surgical treatment for pulmonary metastases from esophageal carcinoma after definitive chemoradiotherapy: Experience from a single institution

Journal of Cardiothoracic Surgery, 2011
Background Surgical treatment for pulmonary metastases is known to be a safe and potentially curative procedure for various primary malignancies. However, there are few reports regarding the prognostic role of surgical treatment for pulmonary metastases ...
Ogawa Hirofumi, Tsubosa Yasuhiro, Sato Hiroshi, Kozu Yoshiki, Yasui Hirofumi, Kondo Haruhiko   +5 more
doaj   +1 more source