Results 51 to 60 of about 1,501,714 (262)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Solution theory of fractional SDEs in complete subcritical regimes
Forum of Mathematics, SigmaWe consider stochastic differential equations (SDEs) driven by a fractional Brownian motion with a drift coefficient that is allowed to be arbitrarily close to criticality in a scaling sense.
Lucio Galeati, Máté Gerencsér
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The therapeutic effect of viscous solution of curcumine in the treatment of recurrent aphthous stomatitis (RAS) [PDF]
Al-Rafidain Dental Journal, 2006 Aim: To determine the various therapeutic effect of different concentrations of viscous curcumine solution on the healing of ulcer in patients with recurrent aphthous stomatitis (RAS).
Maha T Al–Saffar
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Existence of positive solutions for singular eigenvalue problems
Electronic Journal of Differential Equations, 2006 In this paper, we discuss the existence, nonexistence, and multiplicity of positive solutions for a class of singular eigenvalue problems. Some of our theorems are new, while others extend earlier results obtained by Zhang and Kong [12].
Meiqiang Feng, Weigao Ge
doaj
Complete solution of a gauged tensor model [PDF]
Advances in Theoretical and Mathematical Physics, 2019 Building on a strategy introduced in arXiv:1706.05364, we present exact analytic expressions for all the singlet eigenstates and eigenvalues of the simplest non-linear ($n=2, d=3$) gauged Gurau-Witten tensor model. This solves the theory completely. The ground state eigenvalue is $-2\sqrt{14}$ in suitable conventions.
Krishnan, Chethan, Kumar, K. V. Pavan
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Advances in Difference Equations, 2018 This paper is concerned with the approximate controllability and complete controllability of semilinear fractional functional differential systems with control involving Caputo fractional derivative.
Yanhua Wen, Xian-Feng Zhou
doaj +1 more source
Advanced Electronic Materials, 2023 The limits of transistor scaling and digital architectures are encouraging research into new electronic materials, devices, and systems to meet growing computing demands.
Mansi Patel +5 more
doaj +1 more source