Results 41 to 50 of about 1,501,714 (262)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

AviTrap: A novel solution to achieve complete biotinylation.

open access: yesPLoS ONE
Site specific biotinylation of AviTagged recombinant proteins using BirA enzyme is a widely used protein labeling technology. However, due to the incomplete biotinylation reactions and the lack of a purification method specific for the biotinylated ...
Cheng Lu   +12 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Periodic random attractors for stochastic Navier-Stokes equations on unbounded domains

open access: yesElectronic Journal of Differential Equations, 2012
This article concerns the asymptotic behavior of solutions to the two-dimensional Navier-Stokes equations with both non-autonomous deterministic and stochastic terms defined on unbounded domains.
Bixiang Wang
doaj  

Symbolic Solution to Complete Ordinary Differential Equations with Constant Coefficients

open access: yesJournal of Applied Mathematics, 2013
The aim of this paper is to introduce a symbolic technique for the computation of the solution to a complete ordinary differential equation with constant coefficients.
Juan F. Navarro, Antonio Pérez-Carrió
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The construction of solutions to Zakharov–Kuznetsov equation with fractional power nonlinear terms

open access: yesAdvances in Difference Equations, 2019
In the paper, we study a plasma fluid physical model, namely the Zakharov–Kuznetsov (ZK, for simplicity) equation with fractional power nonlinear terms by the complete discrimination system for polynomial method, and give a detailed construction of all ...
Yang Liu, Xin Wang
doaj   +1 more source

Complete Asymptotics for Solution of Singularly Perturbed Dynamical Systems with Single Well Potential

open access: yesMathematics, 2020
We consider a singularly perturbed boundary value problem ( − ε 2 ∆ + ∇ V · ∇ ) u ε = 0 in Ω , u ε = f on ∂ Ω , f ∈ C ∞ ( ∂ Ω ) .
Denis I. Borisov, Oskar A. Sultanov
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Home - About - Disclaimer - Privacy