Results 81 to 90 of about 4,406,015 (337)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
DTCNS: A python toolbox for digital twin-oriented complex networked systems
Digital Twin-Oriented Complex Networked System (DT-CNS) is a modelling paradigm aiming at the representation and analysis of real-world networked systems.
Jiaqi Wen +2 more
doaj +1 more source
Robustness of higher-order networks with synergistic protection
From chemical reactions to human communications, higher-order interactions are ubiquitous in real-world networks. Entities within higher-order interactions often exhibit collective behaviors that could create synergistic effects on robustness of the ...
Qihang Chen +3 more
doaj +1 more source
Complex Adaptive Systems [PDF]
The various groups at the Santa Fe Institute studying complex adaptive systems (CAS) have somewhat different points of view and have adopted different vocabularies. Some of us speak of "artificial life" or "artificial social life" or "artificial worlds,"
Gell-Mann, Murray
core
Transforming a linear module into an adaptive one : tackling the challenge [PDF]
Every learner is fundamentally different. However, few courses are delivered in a way that is tailored to the specific needs of each student. Delivery systems for adaptive educational hypermedia have been extensively researched and found promising. Still,
Cristea, Alexandra I. +1 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Climate-smart agriculture (CSA) conceptually has the potential to contribute to the sustainable development goals of achieving zero hunger, reducing land degradation, eliminating poverty, tackling climate change, and promoting gender equality.
Renata Jagustović +5 more
semanticscholar +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Theory of deferred action: Agent-based simulation model for designing complex adaptive systems [PDF]
Deferred action is the axiom that agents act in emergent organisation to achieve predetermined goals. Enabling deferred action in designed artificial complex adaptive systems like business organisations and IS is problematical.
Eldabi, T, Khan, T, Patel, NV
core

