Results 31 to 40 of about 49,297 (181)
Fusion Genes and RNAs in Cancer Development
Non-Coding RNA, 2021 Fusion RNAs are a hallmark of some cancers. They result either from chromosomal rearrangements or from splicing mechanisms that are non-chromosomal rearrangements.
Kenzui Taniue, Nobuyoshi Akimitsu
doaj +1 more source
Comparative studies of X chromosomes in Cervidae family
Scientific Reports, 2023 The family Cervidae is the second most diverse in the infraorder Pecora and is characterized by variability in the diploid chromosome numbers among species.
Anastasia A. Proskuryakova +8 more
doaj +1 more source
Complex chromosomal rearrangements: origin and meiotic behavior [PDF]
Human Reproduction Update, 2011 Complex chromosomal rearrangements (CCRs) describe structural rearrangements, essentially translocations, involving at least three breakpoints on two or more chromosomes. Although they are rare in humans, their clinical identification is important since CCR carriers can display various phenotypes which include phenotypically normal subjects, infertile ...
F, Pellestor +6 more
openaire +2 more sources
Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases. [PDF]
PLoS Genetics, 2012 DNA double-strand break (DSB) repair occurring in repeated DNA sequences often leads to the generation of chromosomal rearrangements. Homologous recombination normally ensures a faithful repair of DSBs through a mechanism that transfers the genetic ...
Benjamin Pardo, Andrés Aguilera
doaj +1 more source
Animals, 2022 Chromosomal rearrangements can directly influence population differentiation and speciation. The Liolaemus monticola complex in Chile is a unique model consisting of several chromosome races arranged in a latitudinal sequence of increasing karyotype ...
Madeleine Lamborot +4 more
doaj +1 more source
Asian Journal of Andrology, 2022 Apparently balanced chromosomal structural rearrangements are known to cause male infertility and account for approximately 1% of azoospermia or severe oligospermia.
Matthew Hoi Kin Chau +9 more
doaj +1 more source
Engineering chromosome rearrangements in cancer
Disease Models & Mechanisms, 2021 The identification of large chromosomal rearrangements in cancers has multiplied exponentially over the last decade. These complex and often rare genomic events have traditionally been challenging to study, in part owing to lack of tools that efficiently
Salvador Alonso, Lukas E. Dow
doaj +1 more source
Complex chromosome rearrangements: Report of three patients [PDF]
Japanese journal of human genetics, 1988 Three unrelated patients are described, each with a complex,de novo chromosome rearrangement involving four or more break points. One of the patients had few clinical abnormalities and an apparently balanced karyotype with seven break points (1q32, 2q37, 3q26.2, 5q11.2, 5q15, 6q25, 10p13) in six derivative chromosomes.
T, Kamei +5 more
openaire +2 more sources
Array-CGH and multipoint FISH to decode complex chromosomal rearrangements
BMC Genomics, 2006 Background Recently, several high-resolution methods of chromosome analysis have been developed. It is important to compare these methods and to select reliable combinations of techniques to analyze complex chromosomal rearrangements in tumours.
Dumanski Jan +7 more
doaj +1 more source
Chromosomal rearrangements between serotype A and D strains in Cryptococcus neoformans. [PDF]
PLoS ONE, 2009 Cryptococcus neoformans is a major human pathogenic fungus that can cause meningoencephalitis in immunocompromised hosts. It contains two divergent varieties, var. grubii (serotype A) and var.
Sheng Sun, Jianping Xu
doaj +1 more source