Results 161 to 170 of about 3,956,385 (292)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Tracking the Complex Dynamics of Electron-Transfer-Mediated Decay in Real Space and Time. [PDF]

J Am Chem Soc
Trinter F, Hofierka J, Rist J, Kircher M, Weller M, Melzer N, Tsitsonis D, Geyer A, Kruse J, Kastirke G, Williams JB, Miteva T, Dörner R, Schöffler MS, Kunitski M, Sisourat N, Cederbaum LS, Jahnke T.   +17 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Cell stress activates γ9δ2 T cells via endogenous phosphoantigens and butyrophilin complex dynamics. [PDF]

Biomed Pharmacother
Jin Y, Nguyen K, Bashir S, Pawge G, Strand RM, Hsiao CC, Vinogradova O, Wiemer AJ.   +7 more
europepmc   +1 more source

Complex Dynamics of a Cournot Quantum Duopoly Game with Memory and Heterogeneous Players. [PDF]

Entropy (Basel), 2022
Garcia-Perez L, Grau-Climent J, Alonso-Sanz R, Losada JC.   +3 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Complex dynamics of glutamate-induced calcium responses in astrocytes from the nucleus of the solitary tract of mice. [PDF]

Braz J Med Biol Res
Souza MM, Zacharias LR, Leão RM.
europepmc   +1 more source

Antibiotic resistance gene sequencing is necessary to reveal the complex dynamics of immigration from sewers to activated sludge. [PDF]

Front Microbiol, 2023
Gibson C, Kraemer SA, Klimova N, Guo B, Frigon D.   +4 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Exploring complex dynamics in nonlinear Riemann wave models using fractional calculus-based expansion. [PDF]

Sci Rep
Mumtaz A, Masood K, Shakeel M, Shah NA.
europepmc   +1 more source