Results 141 to 150 of about 1,254,353 (318)

Assessing spatial patterns of carbon and nutrient dynamics in catchments of complex topography [PDF]

The topography of a landscape regulates the spatial distribution of water and energy fluxes, which are main drivers of vegetation and soil carbon and nutrient dynamics.
Fatichi, Simone, Bonetti, Sara, Lian, Taiqi, Stähli, Manfred   +3 more
core   +1 more source

A new Zymomonas mobilis platform strain for the efficient production of chemicals

Microbial Cell Factories
Background Zymomonas mobilis is well known for its outstanding ability to produce ethanol with both high specific productivity and with high yield close to the theoretical maximum.
Jonas Frohwitter, Gerrich Behrendt, Steffen Klamt, Katja Bettenbrock   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A system dynamics approach towards nearly zero energy districts [PDF]

The transition to near-zero energy districts is shaped by a complex interplay of stakeholder interests, technological complementarities, and market dynamics.
Zapata Riveros, Juliana, Ulli-Beer, Silvia   +1 more
core  

Molecular dynamics simulations of complex systems including HIV-1 protease [PDF]

, 2010
Advances in supercomputer architectures have resulted in a situation where many scienti fic codes are used on systems whose performance characteristics di ffer considerably from the platform they were developed and optimised for.
Kenway, O.A., Kenway, OA
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Toward Understanding Polar Heat Transport Enhancement in Subglacial Oceans on Icy Moons

Geophysical Research Letters
The interior oceans of several icy moons are considered as affected by rotation. Observations suggest a larger heat transport around the poles than at the equator.
Robert Hartmann, Richard J. A. M. Stevens, Detlef Lohse, Roberto Verzicco   +3 more
doaj   +1 more source