Results 131 to 140 of about 1,254,353 (318)

A bright future for system dynamics: From art to computational science and beyond [PDF]

open access: yes, 2012
This paper presents a bright future for quantitative System Dynamics Modeling. This future relates to all major issues and grand challenges which all happen to be dynamically complex and deeply uncertain.
Kwakkel, J.H. (author)   +3 more
core  

Language dynamics [PDF]

open access: yes, 2012
Thirty authors of different disciplines, ranging from cognitive science and linguistics to mathematics and physics, address the topic of language origin and evolution. Language dynamics is investigated through an interdisciplinary effort, involving field
LORETO, Vittorio   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Control of complex networks requires both structure and dynamics [PDF]

open access: yes, 2015
The study of network structure has uncovered signatures of the organization of complex systems. However, there is also a need to understand how to control them; for example, identifying strategies to revert a diseased cell to a healthy state, or a ...
Luis M. Rocha, Alexander J. Gates
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Launch dynamics modeling and simulation of box-type multiple launch rocket system considering plane clearance contact

open access: yesDefence Technology
As the performance of the box-type multiple launch rocket system (BMLRS) improves, its mechanical structures, particularly the plane clearance design between the slider on the rocket and the guide inside the launch canister, have grown increasingly ...
Jinxin Tang   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design, Modeling, and Vibration Control of a Damper Based on Magnetorheological Fluid and Elastomer

open access: yesActuators
The aim of this study is to propose a damper based on magnetorheological (MR) fluid and elastomer for application in vehicle engine mounting systems to dissipate the vibration energy transferred from the engine to the vehicle body.
Zhuang Jin   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The dynamics of a two‐ class growth model with optimal saving and switch in behavior [PDF]

open access: yes, 2019
We present a two-class economy where capitalists and workers live two periods. Workers may change their saving behaviour depending on their level of wealth.
Commendatore p
core  

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