Results 121 to 130 of about 1,254,353 (318)
Human Vaccines & ImmunotherapeuticsInfluenza remains a serious global health concern, causing significant morbidity and mortality each year. Vaccination is crucial to mitigate its impact, but requires rapid and efficient manufacturing strategies to handle timing and supply.
Tilia Zinnecker +2 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Mechanisms in Dynamically Complex Systems [PDF]
, 2011 In recent debates mechanisms are often discussed in the context of ‘complex systems’ which are understood as having a complicated compositional structure.
Meinard Kuhlmann, Kuhlmann, Meinard
core +1 more source
Sensitivity analysis of vibration characteristics and dynamic responses of a tracked vehicle
Defence TechnologyThis study aims to establish an integrated sensitivity analysis framework for optimization and design of the dynamic performance of mechanical systems such as tracked vehicles, by combining the direct differentiation method (DDM) with the linear ...
Xun Wang +5 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Complex contagion leads to complex dynamics in models coupling behaviour and disease [PDF]
, 2018 Models coupling behaviour and disease as two unique but interacting contagions have existed since the mid 2000s. In these coupled contagion models, behaviour is typically treated as a ‘simple contagion’. However, the means of behaviour spread may in fact
Wang, Xueying +5 more
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Nature Communications, 2017 Coupling of growth and product synthesis is an important principle in metabolic engineering, but its range of applicability is unclear. Here, the authors use a dedicated computational framework to study the feasibility of coupling the production of ...
Axel von Kamp, Steffen Klamt
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Algebraic dynamics from topological and holomorphic dynamics [PDF]
, 2018 Let f:S^2 —> S^2 be a postcritically finite branched covering from the 2-sphere to itself with postcritical set P. Thurston studied the dynamics of f using an induced holomorphic self-map T(f) of the Teichmuller space of complex structures on (S^2, P ...
Ramadas, Rohini
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source