Results 1 to 10 of about 73,359 (140)

Complex interactions between human myoblasts and the surrounding 3D fibrin-based matrix. [PDF]

PLoS ONE, 2012
Anchorage of muscle cells to the extracellular matrix is crucial for a range of fundamental biological processes including migration, survival and differentiation.
Stéphane Chiron, Carole Tomczak, Alain Duperray, Jeanne Lainé, Gisèle Bonne, Alexandra Eder, Arne Hansen, Thomas Eschenhagen, Claude Verdier, Catherine Coirault   +9 more
doaj   +4 more sources

Biologic Augmentation for Meniscus Repair: A Narrative Review [PDF]

Bioengineering
Meniscal preservation is increasingly recognized as a critical determinant of long-term knee joint health, yet successful repair remains challenging due to the meniscus’s limited intrinsic healing capacity.
Tsung-Lin Lee, Scott Rodeo
doaj   +2 more sources

Fibrinogen and Fibrin as Growth Factor Regulators: Pathological Implications, and Translational Opportunities [PDF]

Biomolecules
Fibrinogen and fibrin are multifunctional plasma proteins that play central roles in hemostasis, tissue repair, and extracellular matrix organization. Their complex molecular architecture enables specific interactions with key growth factors, including ...
Abha Sahni, Sanjeev K. Sahni
doaj   +2 more sources

Effect of platelet-rich fibrin matrix in complex with artificial material Nubiplant on expression of chondrogenic marker genes and morphogenesis of the nucleus pulposus cells of intervertebral discs in rats

Ukrainian Neurosurgical Journal, 2020
The purpose was to study the barrier and biological properties of platelet-rich fibrin matrix (PRFM), an artificial biopolymer Nubiplant, and a mixture of PRFM / Nubiplant by assessing the viability and morphological characteristics of nucleus
Eugene G. Pedachenko, Iryna G. Vasylieva, Mykhaylo V. Khyzhnyak, Natalia G. Chopyk, Natalia P. Oleksenko, Iryna M. Shuba, Olga I. Tsjubko, Olena S. Galanta, Anzhela B. Dmytrenko, Tetiana A. Makarova   +9 more
doaj   +2 more sources

Mesothelial Cells in Fibrosis: Focus on Intercellular Crosstalk [PDF]

Biomolecules
Mesothelial cells line serosal cavities and internal organs, playing a vital role in maintaining serosal integrity and homeostasis. Their remarkable plasticity and ability to undergo mesothelial-to-mesenchymal transition (MMT) position them as key ...
Nadezhda Bakalenko, Evdokiya Kuznetsova, Konstantin Dergilev, Irina Beloglazova, Anna Malashicheva   +4 more
doaj   +2 more sources

Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing

Frontiers in Immunology, 2023
IntroductionWound healing is a complex process to restore homeostasis after injury and insufficient skin wound healing is a considerable problem in medicine.
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Mostafa EzEldeen, Estefania Ugarte-Berzal, Erik Martens, Bert Malengier-Devlies, Jennifer Vandooren, Jan Jeroen Vranckx, Jan Jeroen Vranckx, Patrick Matthys, Ghislain Opdenakker   +10 more
doaj   +1 more source

Novel fibrin-fibronectin matrix accelerates mice skin wound healing

Bioactive Materials, 2020
Plasma fibrinogen (F1) and fibronectin (pFN) polymerize to form a fibrin clot that is both a hemostatic and provisional matrix for wound healing. About 90% of plasma F1 has a homodimeric pair of γ chains (γγF1), and 10% has a heterodimeric pair of γ and ...
Carlos Poblete Jara, Ou Wang, Thais Paulino do Prado, Ayman Ismail, Frank Marco Fabian, Han Li, Licio A. Velloso, Mark A. Carlson, William Burgess, Yuguo Lei, William H. Velander, Eliana P. Araújo   +11 more
doaj   +1 more source

Cell-matrix reciprocity in 3D culture models with nonlinear elasticity

Bioactive Materials, 2022
Three-dimensional (3D) matrix models using hydrogels are powerful tools to understand and predict cell behavior. The interactions between the cell and its matrix, however is highly complex: the matrix has a profound effect on basic cell functions but ...
Kaizheng Liu, Maury Wiendels, Hongbo Yuan, Changshun Ruan, Paul H.J. Kouwer   +4 more
doaj   +1 more source

A Combined In Vitro Imaging and Multi-Scale Modeling System for Studying the Role of Cell Matrix Interactions in Cutaneous Wound Healing. [PDF]

PLoS ONE, 2016
Many cell types remodel the extracellular matrix of the tissues they inhabit in response to a wide range of environmental stimuli, including mechanical cues.
Aribet M De Jesus, Maziar Aghvami, Edward A Sander   +2 more
doaj   +1 more source

New strategy of personalized tissue regeneration: when autologous platelet concentrates encounter biomaterials

Frontiers in Bioengineering and Biotechnology, 2023
Components in blood play an important role in wound healing and subsequent tissue regeneration processes. The fibrin matrix and various bioactive molecules work together to participate in this complex yet vital biological process.
Sicong Ren, Sicong Ren, Hanchi Wang, Hanchi Wang, Sijia Ma, Jing Zhou, Jingjie Zhai, Yuemeng Zhu, Yuemeng Zhu, Sheng Chen, Sheng Chen, Siyu Chen, Siyu Chen, Kewen Jia, Kewen Jia, Wenzhou Xu, Yanmin Zhou   +16 more
doaj   +1 more source