Results 11 to 20 of about 43,129 (212)

New strategy of personalized tissue regeneration: when autologous platelet concentrates encounter biomaterials

Frontiers in Bioengineering and Biotechnology, 2023
Components in blood play an important role in wound healing and subsequent tissue regeneration processes. The fibrin matrix and various bioactive molecules work together to participate in this complex yet vital biological process.
Sicong Ren, Sicong Ren, Hanchi Wang, Hanchi Wang, Sijia Ma, Jing Zhou, Jingjie Zhai, Yuemeng Zhu, Yuemeng Zhu, Sheng Chen, Sheng Chen, Siyu Chen, Siyu Chen, Kewen Jia, Kewen Jia, Wenzhou Xu, Yanmin Zhou   +16 more
doaj   +1 more source

Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application

International Journal of Dentistry, 2021
Regenerative endodontics has introduced numerous procedures such as pulp implantation, revascularization, and postnatal stem cell therapy. Revascularization has been successfully implemented clinically nowadays, thus providing dentists with outrageous ...
Sohaib Arshad, Fatima Tehreem, Muhammad Rehab khan, Fatima Ahmed, Anand Marya, Mohmed Isaqali Karobari   +5 more
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3D bioprinting of hepatocytes: core–shell structured co-cultures with fibroblasts for enhanced functionality

Scientific Reports, 2021
With the aim of understanding and recapitulating cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model, a co-culture system using 3D extrusion bioprinting was developed.
Rania Taymour, David Kilian, Tilman Ahlfeld, Michael Gelinsky, Anja Lode   +4 more
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Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model

Journal of Functional Biomaterials, 2018
(1) Background: Intervertebral disc (IVD) repair represents a major challenge. Using functionalised biomaterials such as silk combined with enforced hydrogels might be a promising approach for disc repair.
Daniela A. Frauchiger, Rahel D. May, Ezgi Bakirci, Adel Tekari, Samantha C. W. Chan, Michael Wöltje, Lorin M. Benneker, Benjamin Gantenbein   +7 more
doaj   +1 more source

Natural Bio-Inks for 3D Bioprinting of Cancer Tumor Models

Proceedings, 2020
The engineering of convenient three-dimensional (3D) in vitro tumor models presents many challenges, but they are increasingly identifying as one of the best preclinical drug-screening platforms and a developed method to research cancer in controlled ...
Tuğrul Tolga Demirtaş
doaj   +1 more source

Role of Sticky Bone in Regeneration of Bony Defects in Periodontitis: A Clinical Case Series [PDF]

International Journal of Scientific Research in Dental and Medical Sciences
Periodontitis leads to progressive destruction of periodontal structures, often necessitating regenerative interventions. Injectable Platelet-Rich Fibrin (i-PRF), combined with bone grafts to form "sticky bone", is emerging as a promising regenerative ...
SHIJNA ASHRAF, Jeswin Johnson, Rekha Radhakrishnan, Baiju Madhavan, Neethu Reghu, Santhosh S   +5 more
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A Novel Leptospira interrogans Protein LIC13086 Inhibits Fibrin Clot Formation and Interacts With Host Components

Frontiers in Cellular and Infection Microbiology, 2021
Leptospirosis is a neglected zoonosis, caused by pathogenic spirochetes bacteria of the genus Leptospira. The molecular mechanisms of leptospirosis infection are complex, and it is becoming clear that leptospires express several functionally redundant ...
Felipe José Passalia, Felipe José Passalia, Marcos Bryan Heinemann, Mônica Larucci Vieira, Ana Lucia T. O. Nascimento   +4 more
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Urokinase plasminogen receptor and the fibrinolytic complex play a role in nerve repair after nerve crush in mice, and in human neuropathies.

PLoS ONE, 2012
Remodeling of extracellular matrix (ECM) is a critical step in peripheral nerve regeneration. In fact, in human neuropathies, endoneurial ECM enriched in fibrin and vitronectin associates with poor regeneration and worse clinical prognosis.
Cristina Rivellini, Giorgia Dina, Emanuela Porrello, Federica Cerri, Marina Scarlato, Teuta Domi, Daniela Ungaro, Ubaldo Del Carro, Alessandra Bolino, Angelo Quattrini, Giancarlo Comi, Stefano C Previtali   +11 more
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Polymeric Scaffolds for Dental, Oral, and Craniofacial Regenerative Medicine

Molecules, 2021
Dental, oral, and craniofacial (DOC) regenerative medicine aims to repair or regenerate DOC tissues including teeth, dental pulp, periodontal tissues, salivary gland, temporomandibular joint (TMJ), hard (bone, cartilage), and soft (muscle, nerve, skin ...
David T. Wu, Jose G. Munguia-Lopez, Ye Won Cho, Xiaolu Ma, Vivian Song, Zhiyue Zhu, Simon D. Tran   +6 more
doaj   +1 more source

Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix

International Journal of Cell Biology, 2013
Angiogenesis is a highly regulated event involving complex, dynamic interactions between microvascular endothelial cells and extracellular matrix (ECM) proteins. Alteration of ECM composition and architecture is a hallmark feature of wound clot and tumor
Xiaodong Feng, Marcia G. Tonnesen, Shaker A. Mousa, Richard A. F. Clark   +3 more
doaj   +1 more source