Results 21 to 30 of about 6,670,983 (235)

Mechanical Stability and Fibrinolytic Resistance of Clots Containing Fibrin, DNA, and Histones [PDF]

open access: yes, 2013
Neutrophil extracellular traps are networks of DNA and associated proteins produced by nucleosome release from activated neutrophils in response to infection stimuli and have recently been identified as key mediators between innate immunity, inflammation,
Szabó, László   +23 more
core   +1 more source

Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix

open access: yesInternational Journal of Cell Biology, 2013
Angiogenesis is a highly regulated event involving complex, dynamic interactions between microvascular endothelial cells and extracellular matrix (ECM) proteins. Alteration of ECM composition and architecture is a hallmark feature of wound clot and tumor
Xiaodong Feng   +3 more
doaj   +1 more source

De novo Vessel Formation Through Cross-Talk of Blood-Derived Cells and Mesenchymal Stromal Cells in the Absence of Pre-existing Vascular Structures

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
BackgroundThe generation of functional blood vessels remains a key challenge for regenerative medicine. Optimized in vitro culture set-ups mimicking the in vivo perivascular niche environment during tissue repair may provide information about the ...
Beate M. Rüger   +8 more
doaj   +1 more source

PRF a novel acumen for managing post-Surgical defects after removal of mandibular third molars: A case report

open access: yesJournal of Head & Neck Physicians and Surgeons, 2014
Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue.
Aruna Tambuwala   +3 more
doaj   +2 more sources

Novel applications of biomaterials in the management of parastomal hernia and anal fistula [PDF]

open access: yes, 2010
MD (res)The aim of this thesis was to explore novel applications for both traditional and contemporary biomaterials in the management of parastomal hernia and anal fistula.
Hammond, Toby Mark
core   +4 more sources

Fabrication of Blood Capillary Models for Live Imaging Microarray Analysis

open access: yesMicromachines, 2020
Conventional microarray analysis usually deals with the monolayer or two-dimensional (2D) assays for the high-throughput screening applications. Even though these cell-based assays are effective for preliminary screening at least to have information on ...
Muhammad Asri Abdul Sisak   +4 more
doaj   +1 more source

Fibrin-Enriched Cardiac Extracellular Matrix Hydrogel Promotes In Vitro Angiogenesis

open access: yes, 2023
Angiogenesis is essential for cardiac repair after myocardial infarction. Promoting angiogenesis has been demonstrated as an effective approach for myocardial infarction treatment.
Rubia Shaik (8355921)   +9 more
core   +1 more source

Fibrinogen and Fibrin as Growth Factor Regulators: Pathological Implications, and Translational Opportunities

open access: yesBiomolecules
Fibrinogen and fibrin are multifunctional plasma proteins that play central roles in hemostasis, tissue repair, and extracellular matrix organization. Their complex molecular architecture enables specific interactions with key growth factors, including ...
Abha Sahni, Sanjeev K. Sahni
doaj   +1 more source

A systematic literature review of the management of chronic venous ulcers with autologous fibrin matrix with or without growth factors [PDF]

open access: yes, 2021
8 p.Aim: To evaluate available evidence for the effective management of venous leg ulcers with fibrin matrix with or without growth factors. Methods: A systematic review of the literature was performed to evaluate the use of fibrin matrices with or ...
Cantini Ardila, Jorge Ernesto   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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