Results 1 to 10 of about 6,670,983 (235)

Complex interactions between human myoblasts and the surrounding 3D fibrin-based matrix. [PDF]

PLoS ONE, 2012
Anchorage of muscle cells to the extracellular matrix is crucial for a range of fundamental biological processes including migration, survival and differentiation.
Stéphane Chiron, Carole Tomczak, Alain Duperray, Jeanne Lainé, Gisèle Bonne, Alexandra Eder, Arne Hansen, Thomas Eschenhagen, Claude Verdier, Catherine Coirault   +9 more
doaj   +6 more sources

Novel fibrin-fibronectin matrix accelerates mice skin wound healing [PDF]

Bioactive Materials, 2020
Plasma fibrinogen (F1) and fibronectin (pFN) polymerize to form a fibrin clot that is both a hemostatic and provisional matrix for wound healing. About 90% of plasma F1 has a homodimeric pair of γ chains (γγF1), and 10% has a heterodimeric pair of γ and ...
Carlos Poblete Jara, Ou Wang, Thais Paulino do Prado, Ayman Ismail, Frank Marco Fabian, Han Li, Licio A. Velloso, Mark A. Carlson, William Burgess, Yuguo Lei, William H. Velander, Eliana P. Araújo   +11 more
doaj   +4 more sources

Platelet‐rich fibrin matrix as treatment for complex anal fistulae: A 3‐year experience at a tertiary centre [PDF]

Colorectal Disease
Abstract Aim Treatment of complex anal fistulae remains a significant challenge for physicians and patients. A sphincter‐preserving technique with bioactive platelet‐rich fibrin matrix is one option.
Alejandro Lusilla Lopez, Ursula Aho Fält, Pamela Buchwald, Louis Banka Johnson, Olof Grip   +4 more
europepmc   +3 more sources

Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing

Frontiers in Immunology, 2023
IntroductionWound healing is a complex process to restore homeostasis after injury and insufficient skin wound healing is a considerable problem in medicine.
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Mostafa EzEldeen, Estefania Ugarte-Berzal, Erik Martens, Bert Malengier-Devlies, Jennifer Vandooren, Jan Jeroen Vranckx, Jan Jeroen Vranckx, Patrick Matthys, Ghislain Opdenakker   +10 more
doaj   +1 more source

Effect of platelet-rich fibrin matrix in complex with artificial material Nubiplant on expression of chondrogenic marker genes and morphogenesis of the nucleus pulposus cells of intervertebral discs in rats

Ukrainian Neurosurgical Journal, 2020
The purpose was to study the barrier and biological properties of platelet-rich fibrin matrix (PRFM), an artificial biopolymer Nubiplant, and a mixture of PRFM / Nubiplant by assessing the viability and morphological characteristics of nucleus pulposus (NP) cells in rats, as well as the expression level of chondrogenic marker genes during cell ...
Pedachenko, Eugene G., Vasylieva, Iryna G., Khyzhnyak, Mykhaylo V., Chopyk, Natalia G., Oleksenko, Natalia P., Shuba, Iryna M., Tsjubko, Olga I., Galanta, Olena S., Dmytrenko, Anzhela B., Makarova, Tetiana A.   +9 more
openaire   +3 more sources

Cell-matrix reciprocity in 3D culture models with nonlinear elasticity

Bioactive Materials, 2022
Three-dimensional (3D) matrix models using hydrogels are powerful tools to understand and predict cell behavior. The interactions between the cell and its matrix, however is highly complex: the matrix has a profound effect on basic cell functions but ...
Kaizheng Liu, Maury Wiendels, Hongbo Yuan, Changshun Ruan, Paul H.J. Kouwer   +4 more
doaj   +1 more source

A Combined In Vitro Imaging and Multi-Scale Modeling System for Studying the Role of Cell Matrix Interactions in Cutaneous Wound Healing. [PDF]

PLoS ONE, 2016
Many cell types remodel the extracellular matrix of the tissues they inhabit in response to a wide range of environmental stimuli, including mechanical cues.
Aribet M De Jesus, Maziar Aghvami, Edward A Sander   +2 more
doaj   +1 more source

New strategy of personalized tissue regeneration: when autologous platelet concentrates encounter biomaterials

Frontiers in Bioengineering and Biotechnology, 2023
Components in blood play an important role in wound healing and subsequent tissue regeneration processes. The fibrin matrix and various bioactive molecules work together to participate in this complex yet vital biological process.
Sicong Ren, Sicong Ren, Hanchi Wang, Hanchi Wang, Sijia Ma, Jing Zhou, Jingjie Zhai, Yuemeng Zhu, Yuemeng Zhu, Sheng Chen, Sheng Chen, Siyu Chen, Siyu Chen, Kewen Jia, Kewen Jia, Wenzhou Xu, Yanmin Zhou   +16 more
doaj   +1 more source

Platelet-Rich Fibrin Used in Regenerative Endodontics and Dentistry: Current Uses, Limitations, and Future Recommendations for Application

International Journal of Dentistry, 2021
Regenerative endodontics has introduced numerous procedures such as pulp implantation, revascularization, and postnatal stem cell therapy. Revascularization has been successfully implemented clinically nowadays, thus providing dentists with outrageous ...
Sohaib Arshad, Fatima Tehreem, Muhammad Rehab khan, Fatima Ahmed, Anand Marya, Mohmed Isaqali Karobari   +5 more
doaj   +1 more source

3D bioprinting of hepatocytes: core–shell structured co-cultures with fibroblasts for enhanced functionality

Scientific Reports, 2021
With the aim of understanding and recapitulating cellular interactions of hepatocytes in their physiological microenvironment and to generate an artificial 3D in vitro model, a co-culture system using 3D extrusion bioprinting was developed.
Rania Taymour, David Kilian, Tilman Ahlfeld, Michael Gelinsky, Anja Lode   +4 more
doaj   +1 more source