Results 81 to 90 of about 5,847,170 (272)

On some Chebyshev type inequalities for the complex integral

open access: yesRevista Integración, 2019
Assume that f and g are continuous on γ, γ ⊂ C is a piecewise smooth path parametrized by z (t) , t ∈ [a, b] from z (a) = u to z (b) = w with w 6= u, and the complex Chebyshev functional is defined ...
Silvestru Sever Dragomir
doaj  

Modularized Functions of the Fanconi Anemia Core Complex

open access: yesCell Reports, 2014
The Fanconi anemia (FA) core complex provides the essential E3 ligase function for spatially defined FANCD2 ubiquitination and FA pathway activation. Of the seven FA gene products forming the core complex, FANCL possesses a RING domain with demonstrated ...
Yaling Huang   +9 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The complex-symplectic geometry of SL(2,C)-characters over surfaces

open access: yes, 2003
The SL(2)-character variety X of a closed surface M enjoys a natural complex-symplectic structure invariant under the mapping class group G of M. Using the ergodicity of G on the SU(2)-character variety, we deduce that every G-invariant meromorphic ...
Goldman, William M.
core   +2 more sources

The bounded complexity function versus the unbounded complexity function

open access: yesJournal of Mathematical Analysis and Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Qian, Sheng, Sun, Wenxiang, Zhang, Cheng
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Starlike functions of complex order involving q-hypergeometric functions with fixed point

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2014
Recently Kanas and Ronning introduced the classes of starlike and convex functions, which are normalized with f(ksi)=f'(ksi)-1=0, ksi (|ksi|=d) is a fixed point in the open disc U ={z C:|z| 1}.
Kaliappan Vijaya   +2 more
doaj  

Home - About - Disclaimer - Privacy