Results 101 to 110 of about 5,847,170 (272)
How the Replication and Transcription Complex Functions in Jumping Transcription of SARS-CoV-2. [PDF]
Liang J +9 more
europepmc +1 more source
Computational complexity of functions
Partial translation from [Levin 74]; preliminary version is in [Levin 73]
openaire +3 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Complex functions of Gcn5 and Pcaf in development and disease. [PDF]
Koutelou E, Farria AT, Dent SYR.
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On subword complexity functions
The author finds a polynomial formula for the subword complexity function of a cyclic language. A characterization of context-free languages with exponential subword complexity is derived by appropriately using the pumping lemma.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Volume Dimension of Mass Functions in Complex Networks
A novel definition of volume dimension for a mass function based on a sigmoid asymptote is proposed; in particular, we extend the volume dimension of a mass function to define the volume dimensions for nodes and edges in complex networks.
Maria del Carmen Soto-Camacho +3 more
doaj +1 more source
Gene 33/Mig6/ERRFI1, an Adapter Protein with Complex Functions in Cell Biology and Human Diseases. [PDF]
Xu D, Li C.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

