Results 101 to 110 of about 5,847,170 (272)

How the Replication and Transcription Complex Functions in Jumping Transcription of SARS-CoV-2. [PDF]

open access: yesFront Genet, 2022
Liang J   +9 more
europepmc   +1 more source

Computational complexity of functions

open access: yesTheoretical Computer Science, 1996
Partial translation from [Levin 74]; preliminary version is in [Levin 73]
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Complex functions of Gcn5 and Pcaf in development and disease. [PDF]

open access: yesBiochim Biophys Acta Gene Regul Mech, 2021
Koutelou E, Farria AT, Dent SYR.
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

On subword complexity functions

open access: yesDiscrete Applied Mathematics, 1984
The author finds a polynomial formula for the subword complexity function of a cyclic language. A characterization of context-free languages with exponential subword complexity is derived by appropriately using the pumping lemma.
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Volume Dimension of Mass Functions in Complex Networks

open access: yesMathematics
A novel definition of volume dimension for a mass function based on a sigmoid asymptote is proposed; in particular, we extend the volume dimension of a mass function to define the volume dimensions for nodes and edges in complex networks.
Maria del Carmen Soto-Camacho   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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