Results 141 to 150 of about 15,740,088 (326)
Scaling of optimal-path-lengths distribution in complex networks
Physical Review E, 2005 We study the distribution of optimal path lengths in random graphs with random weights associated with each link (``disorder''). With each link $i$ we associate a weight $ _i = \exp(ar_i)$ where $r_i$ is a random number taken from a uniform distribution between 0 and 1, and the parameter $a$ controls the strength of the disorder.
Kalisk, Tomer +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Complexity of Bounded Length Graph Recoloring
, 2014 We study the following question: Given are two $k$-colorings $ $ and $ $ of a graph $G$ on $n$ vertices, and integer $\ell$. The question is whether $ $ can be modified into $ $, by recoloring vertices one at a time, while maintaining a $k$-coloring throughout, and using at most $\ell$ such recoloring steps.
Bonsma, Paul, Mouawad, Amer E.
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Nodal Statistics of Planar Random Waves
, 2017 We consider Berry's random planar wave model (1977) for a positive Laplace eigenvalue $E>0$, both in the real and complex case, and prove limit theorems for the nodal statistics associated with a smooth compact domain, in the high-energy limit ($E\to ...
Nourdin, Ivan +2 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Scientific DataMitochondrial DNA (mtDNA) mutations are critical to disease research, evolutionary studies, and lineage tracing but are challenging to analyze due to interference from nuclear mitochondrial sequences (NUMTs). Current high-throughput sequencing techniques
Yanan Liu +5 more
doaj +1 more source
Theory of Run-Length Domain Modal Decomposition for Assessing Dynamic Errors in Electricity Meter
IEEE AccessIn scenarios involving photovoltaic power generation and electrical dynamic loads, complex electricity metering signals often exhibit strong randomness and rapid fluctuations.
Ruiming Yuan +5 more
doaj +1 more source