Results 81 to 90 of about 3,295,261 (308)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Abstract Complex networks, which constitute the main subject of network science, have been wide and extensively adopted for representing, characterizing, and modeling an ample range of structures and phenomena from both theoretical and applied perspectives.
openaire +4 more sources
Malleability of complex networks [PDF]
Most complex networks are not static, but evolve along time. Given a specific configuration of one such changing network, it becomes a particularly interesting issue to quantify the diversity of possible unfoldings of its topology. In this work, we suggest the concept of malleability of a network, which is defined as the exponential of the entropy of ...
Filipi Nascimento Silva+2 more
openaire +3 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Data modelling of converters for the automation and monitoring of MTDC grids
Multi-terminal DC (MTDC) grids based on voltage source converters (VSCs) are a promising option to integrate the increasing share of generation from the distributed energy resources (DERs) both in the transmission and distribution grids.
Gaurav Kumar Roy+5 more
doaj +1 more source
Graph Theory in Brain Networks [PDF]
Recent developments in graph theoretic analysis of complex networks have led to deeper understanding of brain networks. Many complex networks show similar macroscopic behaviors despite differences in the microscopic details. Probably two most often observed characteristics of complex networks are scale-free and small-world properties. In this paper, we
arxiv
Complex aperture networks [PDF]
A complex network approach is proposed to study the shear behavior of a rough rock joint. Similarities between aperture profiles are established and a general network in two directions (in parallel and perpendicular to the shear direction) is constructed. Evaluation of this newly formed network shows that the degree distribution of the network, after a
Ghaffari, H.+2 more
openaire +4 more sources
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The advantages of k-visibility: A comparative analysis of several time series clustering algorithms
This paper outlined the advantages of the k-visibility algorithm proposed in [1,2] compared to traditional time series clustering algorithms, highlighting enhanced computational efficiency and comparable clustering quality.
Sergio Iglesias-Perez+2 more
doaj +1 more source
Functions correspond to one of the key concepts in mathematics and science, allowing the representation and modeling of several types of signals and systems. The present work develops an approach for characterizing the coverage and interrelationship between discrete signals that can be fitted by a set of reference functions, allowing the definition of ...
openaire +3 more sources