Results 81 to 90 of about 814,413 (282)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Compact Brillouin Fiber Laser Based on Highly Nonlinear Fiber With 51 Double Spacing Channels

open access: yesIEEE Photonics Journal, 2012
A compact multiwavelength Brillouin fiber laser (BFL) with 51 stable double Brillouin frequency shift channels is demonstrated at room temperature. It uses a ring cavity with a 3-dB coupler for separation of odd-ordered and even-ordered Brillouin Stokes (
B. A. Ahmad   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Optimal percolation on multiplex networks

open access: yesNature Communications, 2017
Multiplex networks consist of a collection of interacting layers and occur in social and technological systems. Here Osat et al. investigate optimal percolation which relates to the process of optimally dismantling multiplex networks and show that ...
Saeed Osat, Ali Faqeeh, Filippo Radicchi
doaj   +1 more source

Using Low-Dimensional Manifolds to Map Relationships Between Dynamic Brain Networks

open access: yesFrontiers in Human Neuroscience, 2019
As the field of dynamic brain networks continues to expand, new methods are needed to allow for optimal handling and understanding of this explosion in data.
Mohsen Bahrami   +10 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Synchronization in Time-Varying and Evolving Complex Networks [PDF]

open access: gold, 2020
Gualberto Solı́s-Perales   +2 more
openalex   +1 more source

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