Results 61 to 70 of about 267,312 (266)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Complex Symmetric Formulation of Maxwell Equations for Fields and Potentials

open access: yesMathematics, 2018
Maxwell equations have two types of asymmetries between the electric and magnetic fields. The first asymmetry is the inhomogeneity induced by the absence of magnetic charge sources. The second asymmetry is due to parity.
George Livadiotis
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Complex trajectories in a classical periodic potential [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2012
This paper examines the complex trajectories of a classical particle in the potential V(x)=-cos(x). Almost all the trajectories describe a particle that hops from one well to another in an erratic fashion. However, it is shown analytically that there are two special classes of trajectories x(t) determined only by the energy of the particle and not by ...
Anderson, Alexander G., Bender, Carl M.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Complex Ga2O3 polymorphs explored by accurate and general-purpose machine-learning interatomic potentials

open access: yesnpj Computational Materials, 2023
Ga2O3 is a wide-band gap semiconductor of emergent importance for applications in electronics and optoelectronics. However, vital information of the properties of complex coexisting Ga2O3 polymorphs and low-symmetry disordered structures is missing.
Junlei Zhao   +5 more
doaj   +1 more source

Isoresonant Complex-valued Potentials and Symmetries [PDF]

open access: yesCanadian Journal of Mathematics, 2011
Abstract Let X be a connected Riemannian manifold such that the resolvent of the free Laplacian , has a meromorphic continuation through . The poles of this continuation are called resonances. When X has some symmetries, we construct complex-valued potentials, V, such that the resolvent of, which has also ameromorphic continuation, has the same ...
openaire   +2 more sources

Classical particle in a complex elliptic potential [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2010
12 pages, 7 ...
Bender, Carl M.   +2 more
openaire   +2 more sources

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