Results 111 to 120 of about 818,733 (341)
FEBS Open Bio, EarlyView.Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy +14 more
wiley +1 more source
A Novel Latin Hypercube Algorithm via Translational Propagation
The Scientific World Journal, 2014 Metamodels have been widely used in engineering design to facilitate analysis and optimization of complex systems that involve computationally expensive simulation programs. The accuracy of metamodels is directly related to the experimental designs used.
Guang Pan, Pengcheng Ye, Peng Wang
doaj +1 more source
DEGENERATION OF ENDOMORPHISMS OF THE COMPLEX PROJECTIVE SPACE IN THE HYBRID SPACE [PDF]
Journal of the Institute of Mathematics of Jussieu, 2018 We consider a meromorphic family of endomorphisms of degree at least 2 of a complex projective space that is parameterized by the unit disk. We prove that the measure of maximal entropy of these endomorphisms converges to the equilibrium measure of the associated non-Archimedean dynamical system when the system degenerates. The convergence holds in the
openaire +4 more sources
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
On projective invariants of the complex Finsler spaces [PDF]
arXiv, 2011 In this paper the projective curvature invariants of a complex Finsler space are obtained. By means of these invariants the notion of complex Douglas space is then defined. A special approach is devoted to obtain the equivalence conditions that a complex Finsler space should be Douglas.
arxiv
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
Asymptotic behaviour of the sectional ring
Comptes Rendus. MathématiqueThe theory of the Okounkov body is a usual tool for analyzing the asymptotic behaviour of the sectional ring of a line bundle over a projective manifold.
Wu, Xiaojun
doaj +1 more source
Projective invariants of CR-hypersurfaces [PDF]
arXiv, 2010 We study the equivalence problem under projective transformation for CR-hypersurfaces of complex projective space. A complete set of projective differential invariants for analytic hypersurfaces is given. The self-dual strongly C-linearly convex hypersurfaces are characterized.
arxiv
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, EarlyView.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source
Holomorphic projection and duality for domains in complex projective space [PDF]
arXiv, 2008 We show that the efficiency of a natural pairing between certain projectively invariant Hardy spaces on dual strongly C-linearly convex real hypersurfaces in complex projective space is measured by the norm of the corresponding Leray transform.
arxiv