Results 111 to 120 of about 131,099 (317)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The spectral rigidity of complex projective spaces, revisited [PDF]

Mathematische Zeitschrift, 2018
28 pages, version 2, some typos ...
openaire   +3 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

A Classification of Compact Cohomogeneity One Locally Conformal Kähler Manifolds

Mathematics
In this paper, we apply a result of the classification of a compact cohomogeneity one Riemannian manifold with a compact Lie group G to obtain a classification of compact cohomogeneity one locally conformal Kähler manifolds.
Daniel Guan
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Toric polar maps, normal crossings and mixed volumes

Comptes Rendus. Mathématique
Given a hypersurface in a complex projective space, we prove that the Chern–Schwartz–MacPherson class of a certain open set, namely the complement of the union of the hypersurface and the coordinate hyperplanes, is given (up to sign) by the multidegrees ...
Fassarella, Thiago, Medeiros, Nivaldo, Salomão, Rodrigo   +2 more
doaj   +1 more source

Berezin Transforms Attached to Landau Levels on the Complex Projective Space P^n(ℂ) [PDF]

, 2021
Nizar Demni, Zouhaı̈r Mouayn, Houda Yaqine, Houda Yaqine   +3 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A Big Picard Theorem for Holomorphic Maps into Complex Projective Space [PDF]

, 2009
YE Ya-sheng, Min Ru
openalex   +1 more source