Results 51 to 60 of about 126,971 (263)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts+8 more
wiley +1 more source
The complex-symplectic geometry of SL(2,C)-characters over surfaces
The SL(2)-character variety X of a closed surface M enjoys a natural complex-symplectic structure invariant under the mapping class group G of M. Using the ergodicity of G on the SU(2)-character variety, we deduce that every G-invariant meromorphic ...
Goldman, William M.
core +2 more sources
On the dynamics characterization of complex projective spaces [PDF]
We show that a closed weakly-monotone symplectic manifold of dimension $2n$ which has minimal Chern number greater than or equal to $n+1$ and admits a Hamiltonian toric pseudo-rotation is necessarily monotone and its quantum homology is isomorphic to that of the complex projective space. As a consequence when $n=2$, the manifold is symplectomorphic to $
openaire +3 more sources
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Geodesic hyperspheres in complex projective space [PDF]
We characterize a geodesic hypersphere by a certain condition on the second fundamental form: Theorem 4.1. Let \(M\) be a real hypersurface in \(P^n\mathbb{C}\), \(n\geq 3\). If the shape operator \(A\) satisfies \[ (R(Y,Z)A)X=0 \] for all tangent vectors \(X\), \(Y\), \(Z\) perpendicular to \(\xi\), then \(M\) is locally congruent to a geodesic ...
openaire +3 more sources
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian+10 more
wiley +1 more source
Pairwise incident planes and hyperkaehler four-folds
We address the following question: what are the cardinalities of maximal finite families of pairwise incident planes in a complex projective space? One proves easily that the span of the planes has dimension 5 or 6. Up to projectivities there is one such
O'Grady, Kieran G.
core
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian+4 more
wiley +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma+10 more
wiley +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source