Results 61 to 70 of about 8,737,420 (298)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
One-dimensional super Calabi-Yau manifolds and their mirrors
Journal of High Energy Physics, 2017 We apply a definition of generalised super Calabi-Yau variety (SCY) to supermanifolds of complex dimension one. One of our results is that there are two SCY’s having reduced manifold equal to ℙ 1 $$ {\mathrm{\mathbb{P}}}^1 $$ , namely the projective ...
S. Noja +4 more
doaj +1 more source
J-approximation of complex projective spaces by lens spaces [PDF]
Pacific Journal of Mathematics, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
The Pontrjagin class of a homotopy complex projective space [PDF]
, 1990 We develop a formula for the Pontrjagin class of a PL homotopy complex projective n-space and offer two applications. If n = 4, 5, or 6, we characterize the Pontrjagin classes of those PL homotopy complex projective n-spaces which admit a locally linear ...
Little, Robert D.
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
DEGENERATION OF ENDOMORPHISMS OF THE COMPLEX PROJECTIVE SPACE IN THE HYBRID SPACE [PDF]
Journal of the Institute of Mathematics of Jussieu, 2018 We consider a meromorphic family of endomorphisms of degree at least 2 of a complex projective space that is parameterized by the unit disk. We prove that the measure of maximal entropy of these endomorphisms converges to the equilibrium measure of the associated non-Archimedean dynamical system when the system degenerates. The convergence holds in the
openaire +3 more sources
Stable hypersurfaces in the complex projective space
, 2020 We characterize the sphere with radius tan 2r= 2 n+ 1 in the complex projective space CPn as the unique stable hypersurface subject to certain bounds on the ...
Righini A., Battaglia E., Monti R.
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source