Results 61 to 70 of about 130,787 (274)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Scanning the moduli of smooth hypersurfaces

open access: yesForum of Mathematics, Sigma
We study the locus of smooth hypersurfaces inside the Hilbert scheme of a smooth projective complex variety. In the spirit of scanning, we construct a map to a continuous section space of a projective bundle, and show that it induces an isomorphism in ...
Alexis Aumonier
doaj   +1 more source

Integrable deformation of ℂP n and generalised Kähler geometry

open access: yesJournal of High Energy Physics, 2020
We build on the results of [1] for generalised frame fields on generalised quotient spaces and study integrable deformations for ℂP n . In particular we show how, when the target space of the Principal Chiral Model is a complex projective space, a two ...
Saskia Demulder   +3 more
doaj   +1 more source

CP2 skyrmions and skyrmion crystals in realistic quantum magnets

open access: yesNature Communications, 2023
Magnetic skyrmions are nanoscale topological textures that have been recently observed in different families of quantum magnets. These objects are called CP1 skyrmions because they are built from dipoles—the target manifold is the 1D complex projective ...
Hao Zhang   +4 more
doaj   +1 more source

DEGENERATION OF ENDOMORPHISMS OF THE COMPLEX PROJECTIVE SPACE IN THE HYBRID SPACE [PDF]

open access: yesJournal of the Institute of Mathematics of Jussieu, 2018
We consider a meromorphic family of endomorphisms of degree at least 2 of a complex projective space that is parameterized by the unit disk. We prove that the measure of maximal entropy of these endomorphisms converges to the equilibrium measure of the associated non-Archimedean dynamical system when the system degenerates. The convergence holds in the
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Differentials of the 2nd kind on a product surface

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1979
This paper deals with the problems of representing an arbitrary double differential of the second kind, defined on a surface which is the topological product of two curves, in terms of the products of simple differentials of the second kind on the two ...
J. C. Wilson
doaj   +1 more source

J-approximation of complex projective spaces by lens spaces [PDF]

open access: yesPacific Journal of Mathematics, 1999
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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