Results 71 to 80 of about 130,787 (274)
OPTIMAL LINE PACKINGS FROM FINITE GROUP ACTIONS
Forum of Mathematics, Sigma, 2020 We provide a general program for finding nice arrangements of points in real or complex projective space from transitive actions of finite groups. In many cases, these arrangements are optimal in the sense of maximizing the minimum distance.
JOSEPH W. IVERSON +2 more
doaj +1 more source
CYJAX: A package for Calabi-Yau metrics with JAX
Machine Learning: Science and Technology, 2023 We present the first version of CYJAX, a package for machine learning Calabi–Yau metrics using JAX. It is meant to be accessible both as a top-level tool and as a library of modular functions.
Mathis Gerdes, Sven Krippendorf
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A Novel Latin Hypercube Algorithm via Translational Propagation
The Scientific World Journal, 2014 Metamodels have been widely used in engineering design to facilitate analysis and optimization of complex systems that involve computationally expensive simulation programs. The accuracy of metamodels is directly related to the experimental designs used.
Guang Pan, Pengcheng Ye, Peng Wang
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On piecewise isomorphism of some varieties
, 2011 Two quasi-projective varieties are called piecewise isomorphic if they can be stratified into pairwise isomorphic strata. We show that the m-th symmetric power $S^m(C^n)$ of the complex affine space $C^n$ is piecewise isomorphic to $C^{mn}$ and the m-th ...
Gusein-Zade, S. M. +2 more
core
On the zeta functions on the projective complex spaces
Analysis, geometry and number theory, 2015 In this article, we study the zeta function $ζ_q$ associated to the Laplace operator $Δ_q$ acting on the space of the smooth $(0,q)$-forms with $q=0,\ldots,n$ on the complex projective space $\mathbb{P}^n(\mathbb{C})$ endowed with its Fubini-Study metric. In particular, we show that the values of $ζ_q$ at non-positive integers are rational.
openaire +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source