Results 81 to 90 of about 3,849 (309)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Ruled Real Hypersurfaces in the Indefinite Complex Projective Space
, 2022 The main two families of real hypersurfaces in complex space forms are Hopf and ruled. However, very little is known about real hypersurfaces in the indefinite complex projective space $\cpn$.
Pérez, Juan de Dios +2 more
core +1 more source
On the Stable Homotopy of Quaternionic and Complex Projective Spaces [PDF]
Proceedings of the American Mathematical Society, 1970 Let the image in H 4 k
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Dynamical branes on expanding orbifold and complex projective space
, 2023 We construct some new dynamical $p$-brane solutions to gravity theories on curved backgrounds. We discuss the relations between dynamical branes, a new time-dependent solution on complex projective space $\mathbb{C}{\rm P}^n$ and the static $p$-branes on
Uzawa, Kunihito, Nitta, Muneto
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A Novel Latin Hypercube Algorithm via Translational Propagation
The Scientific World Journal, 2014 Metamodels have been widely used in engineering design to facilitate analysis and optimization of complex systems that involve computationally expensive simulation programs. The accuracy of metamodels is directly related to the experimental designs used.
Guang Pan, Pengcheng Ye, Peng Wang
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Asymptotic behaviour of the sectional ring
Comptes Rendus. MathématiqueThe theory of the Okounkov body is a usual tool for analyzing the asymptotic behaviour of the sectional ring of a line bundle over a projective manifold.
Wu, Xiaojun
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Real hypersurfaces of a complex projective space
Tsukuba Journal of Mathematics, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source