Results 81 to 90 of about 8,737,420 (298)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
OPTIMAL LINE PACKINGS FROM FINITE GROUP ACTIONS
Forum of Mathematics, Sigma, 2020 We provide a general program for finding nice arrangements of points in real or complex projective space from transitive actions of finite groups. In many cases, these arrangements are optimal in the sense of maximizing the minimum distance.
JOSEPH W. IVERSON +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Real hypersurfaces of a complex projective space
Tsukuba Journal of Mathematics, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Minimal 2-spheres in a complex projective space [PDF]
, 2007 In this paper conformal minimal 2-spheres immersed in a complex projective space are studied by applying Lie theory and moving frames. We give differential equations of Kähler angle and square length of the second fundamental form.
Peng, Jiagui, Jiao, Xiaoxiang
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Killing tensors on complex projective space [PDF]
, 2023 The Killing tensors of arbitrary rank on complex projective space with its Fubini-Study metric are determined and it is shown that these spaces are generated by the Killing fields.Comment: 14 pages.
Eastwood, Michael
core +1 more source
A Novel Latin Hypercube Algorithm via Translational Propagation
The Scientific World Journal, 2014 Metamodels have been widely used in engineering design to facilitate analysis and optimization of complex systems that involve computationally expensive simulation programs. The accuracy of metamodels is directly related to the experimental designs used.
Guang Pan, Pengcheng Ye, Peng Wang
doaj +1 more source