Results 61 to 70 of about 692,833 (333)

The equivariant Atiyah class

open access: yesComptes Rendus. Mathématique, 2021
Let $X$ be a complex scheme acted on by an affine algebraic group $G$. We prove that the Atiyah class of a $G$-equivariant perfect complex on $X$, as constructed by Huybrechts and Thomas, is $G$-equivariant in a precise sense.
Ricolfi, Andrea T.
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh   +5 more
wiley   +1 more source

All (4,0): Sigma models with (4,0) off-shell supersymmetry

open access: yesJournal of High Energy Physics, 2017
Off-shell (4, 0) supermultiplets in 2-dimensions are formulated. These are used to construct sigma models whose target spaces are vector bundles over manifolds that are hyperkähler with torsion.
Chris Hull, Ulf Lindström
doaj   +1 more source

Integrable deformation of ℂP n and generalised Kähler geometry

open access: yesJournal of High Energy Physics, 2020
We build on the results of [1] for generalised frame fields on generalised quotient spaces and study integrable deformations for ℂP n . In particular we show how, when the target space of the Principal Chiral Model is a complex projective space, a two ...
Saskia Demulder   +3 more
doaj   +1 more source

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers   +7 more
wiley   +1 more source

Quadratic Killing tensors on symmetric spaces which are not generated by Killing vector fields

open access: yesComptes Rendus. Mathématique
Every Killing tensor field on the space of constant curvature and on the complex projective space can be decomposed into the sum of symmetric tensor products of Killing vector fields (equivalently, every polynomial in velocities integral of the geodesic ...
Matveev, Vladimir S., Nikolayevsky, Yuri
doaj   +1 more source

On the non-existence of special generic maps on complex projective spaces [PDF]

open access: yesarXiv, 2022
We prove the non-existence of special generic maps on complex projective space as our extended new result. Simplest special generic maps are Morse functions with exactly two singular points on spheres, or Morse functions in Reeb's theorem, and canonical projections of unit spheres.
arxiv  

On the bordism ring of complex projective space [PDF]

open access: yesProceedings of the American Mathematical Society, 1973
The bordism ring M U ∗ ( C P ∞ ) M{U_\ast }(C{P^\infty }) is central to the theory of formal groups as applied by D. Quillen, J. F. Adams, and others recently to complex cobordism. In the present paper,
openaire   +2 more sources

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