Results 61 to 70 of about 3,807 (309)
All (4,0): Sigma models with (4,0) off-shell supersymmetry
Off-shell (4, 0) supermultiplets in 2-dimensions are formulated. These are used to construct sigma models whose target spaces are vector bundles over manifolds that are hyperkähler with torsion.
Chris Hull, Ulf Lindström
doaj +1 more source
Integrable deformation of ℂP n and generalised Kähler geometry
We build on the results of [1] for generalised frame fields on generalised quotient spaces and study integrable deformations for ℂP n . In particular we show how, when the target space of the Principal Chiral Model is a complex projective space, a two ...
Saskia Demulder+3 more
doaj +1 more source
On the bordism ring of complex projective space [PDF]
The bordism ring M U ∗ ( C P ∞ ) M{U_\ast }(C{P^\infty }) is central to the theory of formal groups as applied by D. Quillen, J. F. Adams, and others recently to complex cobordism. In the present paper,
openaire +2 more sources
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
The eigenvalues of β-Laplacian of slant submanifolds in complex space forms
In this paper, we provided various estimates of the first nonzero eigenvalue of the $ \beta $-Laplacian operator on closed orientated $ p $-dimensional slant submanifolds of a $ 2m $-dimensional complex space form $ \widetilde{\mathbb{V}}^{2m}(4\epsilon)
Lamia Saeed Alqahtani, Akram Ali
doaj +1 more source
CP2 skyrmions and skyrmion crystals in realistic quantum magnets
Magnetic skyrmions are nanoscale topological textures that have been recently observed in different families of quantum magnets. These objects are called CP1 skyrmions because they are built from dipoles—the target manifold is the 1D complex projective ...
Hao Zhang+4 more
doaj +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Differentials of the 2nd kind on a product surface
This paper deals with the problems of representing an arbitrary double differential of the second kind, defined on a surface which is the topological product of two curves, in terms of the products of simple differentials of the second kind on the two ...
J. C. Wilson
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source