Results 61 to 70 of about 131,099 (317)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

On the Algebraic Geometry of Multiview

Foundations
We study the multiviews of algebraic space curves X from n pin-hole cameras of a real or complex projective space. We assume the pin-hole centers to be known, i.e., we do not reconstruct them. Our tools are algebro-geometric.
Edoardo Ballico
doaj   +1 more source

The equivariant Atiyah class

Comptes Rendus. Mathématique, 2021
Let $X$ be a complex scheme acted on by an affine algebraic group $G$. We prove that the Atiyah class of a $G$-equivariant perfect complex on $X$, as constructed by Huybrechts and Thomas, is $G$-equivariant in a precise sense.
Ricolfi, Andrea T.
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

All (4,0): Sigma models with (4,0) off-shell supersymmetry

Journal of High Energy Physics, 2017
Off-shell (4, 0) supermultiplets in 2-dimensions are formulated. These are used to construct sigma models whose target spaces are vector bundles over manifolds that are hyperkähler with torsion.
Chris Hull, Ulf Lindström
doaj   +1 more source

CP2 skyrmions and skyrmion crystals in realistic quantum magnets

Nature Communications, 2023
Magnetic skyrmions are nanoscale topological textures that have been recently observed in different families of quantum magnets. These objects are called CP1 skyrmions because they are built from dipoles—the target manifold is the 1D complex projective ...
Hao Zhang, Zhentao Wang, David Dahlbom, Kipton Barros, Cristian D. Batista   +4 more
doaj   +1 more source

Immersions of real projective spaces into complex projective spaces

Hiroshima Mathematical Journal, 1987
This paper achieves a classification up to regular homotopy of immersions from a real projective space \(P^ n({\mathbb{R}})\) into a complex projective space \(P^ m({\mathbb{C}})\). Calculations with characteristic classes show that, for \(n>m\), any such immersion is nullhomotopic.
openaire   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Integrable deformation of ℂP n and generalised Kähler geometry

Journal of High Energy Physics, 2020
We build on the results of [1] for generalised frame fields on generalised quotient spaces and study integrable deformations for ℂP n . In particular we show how, when the target space of the Principal Chiral Model is a complex projective space, a two ...
Saskia Demulder, Falk Hassler, Giacomo Piccinini, Daniel C. Thompson   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source