Results 191 to 200 of about 5,284,283 (273)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Initial Insights into ICD-11 Complex PTSD and Emotional Distress in Emerging Adults in India: Prevalence, Predictors, and Psychosocial Correlates. [PDF]

Indian J Psychol Med
Pandey MK, Shukla S, Mishra P, Murthy S, Rao TSS.   +4 more
europepmc   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Court Child Experts' Experiences in Assessing Parenting Cases Involving Parental Mental Illness

Child &Family Social Work, EarlyView.
ABSTRACT This study explores the experiences of Court Child Experts (CCEs), professionals employed by the Australian family courts, in parenting matters involving parental mental illness. Using interpretative phenomenological analysis, interviews were conducted with five senior CCEs who reflected on their assessment practices, the challenges associated
Taegan A. Holford, Andrea E. Reupert
wiley   +1 more source

Testing the Use of "Clinical Checks" With the International Trauma Questionnaire to Measure PTSD and Complex PTSD. [PDF]

Acta Psychiatr Scand
Shevlin M, Hyland P, Brewin CR, Cloitre M, Karatzias T, Redican E.   +5 more
europepmc   +1 more source

Temporalities of Trauma: An Exploration of the Role of Socio‐Temporal Rhythms in Foster Carer Experiences of Vicarious Trauma

Child &Family Social Work, EarlyView.
ABSTRACT Foster carers raise children whose trauma backgrounds likely result in behaviours that are not simply challenging, but which can also result in vicarious trauma for foster carers. While a growing body of research has explored vicarious trauma among foster carers, to date research has not explored how temporal shifts produced by raising foster ...
Sam Arthurson, Damien W. Riggs, Ben Lohmeyer   +2 more
wiley   +1 more source

Treating complex PTSD with Schema Therapy, ImRs and EMDR: a review and case study. [PDF]

Eur J Psychotraumatol
van Hemert MTC, de Jong PM, Brouwer TR, Zoon L, Gunst E, Claes L, Morrens M.   +6 more
europepmc   +1 more source

Living in Temporary Care: Children's Experiences of Placement Instability in Out‐of‐Home Care—A Thematic Synthesis of a Scoping Review

Child &Family Social Work, EarlyView.
ABSTRACT Placement stability is a central objective in out‐of‐home care, yet many children experience repeated re‐placements. While previous research has largely focused on predictors and outcomes of placement instability, children's own experiences of transient care trajectories remain less explored.
Marian Ådnanes, Vibeke Krane, Ketil Eide, Jannike Kaasbøll, Reidun Follesø, Silje L. Kaspersen, Moses Deyegbe Kuvoame, Mari Gunnes   +7 more
wiley   +1 more source

Through the Maze of Child Mental Health Care: Parents' Experiences and the Role of Social Work

Child &Family Social Work, EarlyView.
ABSTRACT This qualitative study explored parents' experiences of professional care for children with mental health challenges, focusing on the role of social work. Fourteen semi‐structured interviews (mothers: n = 11, fathers: n = 3) were analysed thematically.
Nika Totova, Kristyna Gabova, Zdenek Meier, Radek Trnka   +3 more
wiley   +1 more source

The promise of ICD-11-defined PTSD and complex PTSD to improve care for trauma-exposed populations. [PDF]

World Psychiatry
Cloitre M.
europepmc   +1 more source