Results 121 to 130 of about 8,967,370 (295)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

An Optimality Explanation of Compensatory Lengthening Process in Laki Dialect [PDF]

open access: yesمطالعات زبان‌‌ها و گویش‌های غرب ایران, 2018
the present research is aimed to analyze the compensatory lengthening process in Delfan Laki dialect by the use of optimality theory and it wants to answer this question: Is there compensatory lengthening in complex words or not?
farzane heidari
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ICT-DCU question answering task at NTCIR-6 [PDF]

open access: yes, 2007
This paper describes details of our participation in the NTCIR-6 Chinese-to-Chinese Question Answering task. We use the “retrieval plus extraction approach” to get answers for questions.
Bin Wang   +5 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Improvements to the complex question answering models [PDF]

open access: yes, 2011
x, 128 leaves : ill. ; 29 cmIn recent years the amount of information on the web has increased dramatically. As a result, it has become a challenge for the researchers to find effective ways that can help us query and extract meaning from these large ...
Imam, Md. Kaisar
core  

Factors associated with a positive response to the surprise question in complex chronic patients treated by advanced practice nurses in primary care

open access: yesBMC Palliative Care
Background The “surprise question” (“Would I be surprised if the patient died within the next 12 months?”) is useful to predict the survival of patients and indicate the requirement for further assessment of their palliative care needs.
Rafael Montoya-Juárez   +6 more
doaj   +1 more source

ETR: Event-Centric Temporal Reasoning for Question-Conditioned Video Question Answering

open access: yesMathematics
Video Question Answering (VideoQA) requires a deep understanding of dynamic video content, integrating spatial reasoning, temporal dependencies, and language comprehension.
Lingmin Pan   +8 more
doaj   +1 more source

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