Results 61 to 70 of about 1,217,820 (328)
Finite Element Computations of Complex Stress Intensity Factor Magnitude of Interfacial Crack in Bi-Material Composites [PDF]
International Conference on Aerospace Sciences and Aviation Technology, 2015 Composite structures are distinguished by interfaces separating their different layers. These interfaces represent region of mismatches in mechanical and thermal properties of the adjacent layers. These regions are rich in cracks which are laying either on or sub- the interface in a direction parallel or perpendicular to it.
openaire +1 more source
Finite element analysis of fretting crack propagation
, 2011 In this work, the finite elements method (FEM) is used to analyse the growth of fretting cracks. FEM can be favourably used to extract the stress intensity factors in mixed mode, a typical situation for cracks growing in the vicinity of a fretting ...
Basseville, Stéphanie, Proudhon, Henry
core +3 more sources
Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors. [PDF]
, 2018 During embryogenesis tissue layers undergo morphogenetic flow rearranging and folding into specific shapes. While developmental biology has identified key genes and local cellular processes, global coordination of tissue remodeling at the organ scale ...
Lefebvre, Matthew F +4 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
PLoS ONE, 2020 BackgroundAsthma is a heterogeneous disease of a complex etiology in which genetic, environmental and personality variables are important factors determining the development of complicated strategies related to coping with stress and temperament traits ...
Michał G Panek +2 more
doaj +1 more source
The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins [PDF]
, 2019 Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how cells do counteract spontaneous DNA–RNA hybrids, here we screen an siRNA library covering 240 human DNA damage response (DDR) genes ...
Aguilera López, Andrés +5 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Multiscale correlative tomography: an investigation of creep cavitation in 316 stainless steel [PDF]
, 2017 Creep cavitation in an ex-service nuclear steam header Type 316 stainless steel sample is investigated through a multiscale tomography workflow spanning eight orders of magnitude, combining X-ray computed tomography (CT), plasma focused ion beam (FIB ...
A Delobbe +31 more
core +2 more sources
DNA damage induced during mitosis undergoes DNA repair synthesis. [PDF]
, 2020 Understanding the mitotic DNA damage response (DDR) is critical to our comprehension of cancer, premature aging and developmental disorders which are marked by DNA repair deficiencies.
Berns, Michael W +10 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source