Results 201 to 210 of about 13,893,592 (304)

A complex structure of escaping helium spanning more than half the orbit of the ultra-hot Jupiter WASP-121 b. [PDF]

Nat Commun
Allart R, Coulombe LP, Carteret Y, Splinter J, Dang L, Bourrier V, Lafrenière D, Albert L, Artigau É, Benneke B, Cowan NB, Doyon R, Krishnamurthy V, Jayawardhana R, Johnstone D, Langeveld AB, Meyer MR, Pelletier S, Piaulet-Ghorayeb C, Radica M, Taylor J, Turner JD.   +21 more
europepmc   +1 more source

A gated graph transformer for protein complex structure quality assessment and its performance in CASP15. [PDF]

Bioinformatics, 2023
Chen X, Morehead A, Liu J, Cheng J.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Insights into Catechin-Copper Complex Structure and Biologic Activity Modulation. [PDF]

Molecules
Lungu II, Cioanca O, Mircea C, Tuchilus C, Stefanache A, Huzum R, Hancianu M.   +6 more
europepmc   +1 more source

SnapShot: Mediator complex structure. [PDF]

Cell, 2022
Nayak S, Taatjes DJ.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Challenges of drilling Iran's deepest surface hole in the saddle section of Changuleh oilfield with complex structure and pressure regimes. [PDF]

Sci Rep
Jamshidi E, Saen S, Golshaghagh J, Kianoush P, Adib A, Mohammadi A.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Construction of PROTAC-Mediated Ternary Complex Structure Distribution Profiles Using Extensive Conformational Search. [PDF]

J Chem Inf Model
Kudo G, Hirao T, Harada R, Shigeta Y, Hirokawa T, Yoshino R.   +5 more
europepmc   +1 more source

Effect of dye complex structure on performance in DSSCs; An experimental and theoretical study. [PDF]

Heliyon, 2022
Arjmand F, Rashidi Ranjbar Z, Fatemi E G H.   +2 more
europepmc   +1 more source