Results 151 to 160 of about 2,361,537 (287)

Application of dynamic programming for the analysis of complex water resources systems : a case study on the Mahaweli River basin development in Sri Lanka

, 1992
M.D.U.P. Kularathna
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Accelerating First-Principles Molecular-Dynamics Thermal Conductivity Calculations for Complex Systems. [PDF]

J Chem Theory Comput
Wieser S, Cen YJ, Madsen GKH, Carrete J.
europepmc   +1 more source

Automated Determination of Major and Trace Metals in Biopharmaceutical Samples of Complex Matrix Using Seafast Preparation System Coupled to Inductively Coupled Plasma Mass Spectrometry

Qiang Tu, Wendy Zhong
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Coherence-Gradient Theory: A Unified Framework for Measuring Integrated Stability Across Complex Systems

Emma Dobbin
openalex   +1 more source

Application of systems engineering to complex systems and system of systems

, 2017
Rick Sturdivant, Chong, Edwin K. P., Sega, Ronald M., Jayasumana, Anura P., Atadero, Rebecca   +4 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Network centrality drives optimal protection investment against systemic risk propagation in complex systems. [PDF]

Sci Rep
Park C.
europepmc   +1 more source

Informational Tension Theory: A General Framework for Inferring Latent Entities Through Entropic Deformation in Complex Systems

Matheus Grego
openalex   +1 more source