Results 111 to 120 of about 2,018,314 (300)

Spaces of the Past, Histories of the Present: An Interview with Stuart Elden and Derek Gregory [PDF]

, 2011
The ontologies of space and territory, our experience of them and the techniques we use to govern them, the very conception of the socio-spatial formations that we inhabit, are all historically specific: they depend on a genealogy of practices ...
Elden, Stuart, Gregory, Derek, Sevilla Buitrago, Álvaro   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Emergencia y concurrencia de emociones en el proceso formativo del profesorado de matemáticas Emergency and co-occurrence of emotions in the formative process of mathematics’ teachers

Transformación, 2018
This article presents the results of a doctoral research that explores pupils’ emotional response from an experiential approach. It acknowledges the occurrence of an emotion as produced either by emergency or concurrence.
Jorge Iván Ávila Contreras
doaj  

Developing scientific entrepreneurship and complex thinking skills: creating narrative scripts using ChatGPT

Frontiers in Education
The increased access to artificial intelligence (AI) applications has made it possible to develop more engaging and complex educational activities for students in different disciplines.
Carlos Enrique George-Reyes, Carlos Enrique George-Reyes, Elisa Vilhunen, Raidell Avello-Martínez, Edgar López-Caudana   +4 more
doaj   +1 more source

Implementing innovation and knowledge management in the Romanian economy [PDF]

The purpose of this paper is to present a critical evaluation of the implementation and development of innovation and knowledge management in the Romanian economy.
Constantin Bratianu, Simona Vasilache
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Perceived competency in complex thinking skills among university community members in Pakistan: insights across disciplines

Cogent Education
This article aims to evaluate university community members’ (faculty members and students, in this case) perceptions of their complex thinking competency and its sub-competencies – including systemic, scientific, critical, and innovative thinking ...
José Carlos Vázquez-Parra, Rasikh Tariq, Isolda Margarita Castillo-Martínez, Fawad Naseer   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design interventions, prediction and science in the sustainable transition of large, complex systems, [PDF]

, 2010
The way that human beings live and consume the natural and environmental resources of the planet are not sustainable. Sustainability involves changes in individual beliefs, expectations, values and behaviours at the microlevel, changes in policy at the ...
Dewberry, Emma, Johnson, Jeffrey
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source