Results 201 to 210 of about 10,183,399 (294)

An Explainable Hybrid Machine Learning Approach Based on MPSO-XGBoost for Pest Density Prediction in Almond Orchards. [PDF]

Insects
Barut C, Demirol D, Bingöl H, Yüksel H, Alatas B, Özgen İ.   +5 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Entangled States are Typically Incomparable. [PDF]

Commun Math Phys
Jain V, Kwan M, Michelen M.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Application of machine learning prediction models for in-hospital mortality in diabetic sepsis patients: a study based on the MIMIC IV database. [PDF]

BMC Med Inform Decis Mak
Shen Z, Zhang H, Wang Y.
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

About some properties of jacobian for polynomial mappings of two complex variables

Journal of Applied Mathematics and Computational Mechanics, 2013
Bartosz Gawroński, Julia Jankowska, Rafał Moltzan, Izabela Włodarczyk, Grzegorz Biernat   +4 more
doaj   +1 more source

AI-driven predictive modeling of supercritical CO₂ solubility using cheetah-optimized machine learning. [PDF]

Front Med (Lausanne)
Alorfi AS, Abu-Hamdeh NH.
europepmc   +1 more source