Results 221 to 230 of about 131,850 (307)

Inclusion co-crystals based on Tröger's base molecular box for thermally activated delayed fluorescence. [PDF]

Nat Commun
Wang Y, Liu K, Li Y, Zheng Z, Shang Y, Li B, He H, Li C.   +7 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Heavy metal contamination in groundwater: sources and sustainable remediation approaches: a review. [PDF]

RSC Adv
Hama Aziz KH, Noori Nawzad R, Star H.
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Cyclodextrin-Based Delivery Systems in Cosmeceuticals: Current Advances and Future Perspectives. [PDF]

Biomolecules
Amaro C, Kowalczyk T, Picot L, Merecz-Sadowska A, Verdugo P, Cabral-Marques H, Sitarek P.   +6 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Molecular Recognition by Halogen Bonding With Atomic Precision in a Covalent Organic Cage. [PDF]

Angew Chem Int Ed Engl
Dupin PA, Yang J, Antonetti E, Chatelet B, Bugaut X, Dutasta JP, Nava P, Manick AD, Bardelang D, Martinez A.   +9 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Amorphous pyrano[3,2-c]quinoline-semicarbazone thin films switch from uniform to heterogeneous morphology and optical modulation upon copper coordination. [PDF]

Sci Rep
El-Saady AA, Ibrahim MA, Mansour AM, El-Nahass MM, Adly OMI, Farag AAM.   +5 more
europepmc   +1 more source