Results 181 to 190 of about 5,924,258 (339)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Is Complexity an Illusion?

Simplicity is held by many to be the key to general intelligence. Simpler models tend to “generalise”, identifying the cause or generator of data with greater sample efficiency. The implications of the correlation between simplicity and generalisation extend far beyond computer science, addressing questions of physics and even biology.
openaire   +2 more sources

Computational complexity of LCPs associated with positive definite symmetric matrices [PDF]

, 1979
Yahya Fathi
openalex   +1 more source

Lost giants, lost functions: palaeodietary insights into the ecological niches of Pleistocene ground sloths. [PDF]

Biol Lett
Kurre A, DeSantis LRG.
europepmc   +1 more source

Complexity And Causation [PDF]

, 2007
Burke, Timothy
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

The rat’s long-term preference for complexity in its environment [PDF]

, 1975
Michael S. Denny
openalex   +1 more source

Assessing ChatGPT-4 as a clinical decision support tool in neuro-oncology radiotherapy: a prospective comparative study. [PDF]

J Neurooncol
Tini P, Novi F, Donnini F, Perrella A, Bagnacci G, Mazzei MA, Minniti G.   +6 more
europepmc   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

The influence of surface complexity on judgments of area [PDF]

, 1970
Ronald T. Verrillo, Christopher K. Graeff   +1 more
openalex   +1 more source