Results 211 to 220 of about 5,765,386 (368)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Understanding local connectivity and complexity in the skeleton of deforestation. [PDF]

Sci Rep
Urgilez-Clavijo A, Rivas-Tabares DA, Gobin A, Tarquis Alfonso AM, de la Riva Fernández J.   +4 more
europepmc   +1 more source

That Complex Complex

Gastroenterology, 1980
openaire   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

On the optimal layout of (K_p - C_p)ⁿ into grid and certain structures. [PDF]

Sci Rep
Vincy GC, Micheal DR.
europepmc   +1 more source

Relations Among Complexity Measures [PDF]

, 1979
Nicholas Pippenger, Michael J. Fischer
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Retracted: Optimization of Online Teaching Quality Evaluation Model Based on Hierarchical PSO-BP Neural Network

Complexity, 2023
null Complexity
doaj   +1 more source

Resilience-focused debriefing: addressing complexity in interprofessional simulation-based education-a design-based research study. [PDF]

Adv Simul (Lond)
Amorøe TN, Rystedt H, Oxelmark L, Dieckmann P, Andréll P.   +4 more
europepmc   +1 more source

Measurement of the Sequence Complexity of Cloned Moloney Murine Leukemia Virus 60 to 70 S RNA: Evidence for a Haploid Genome [PDF]

, 1974
Hung Fan, Michael Paskind
openalex   +1 more source