Results 61 to 70 of about 5,924,258 (339)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Quantifying the impact of homophily and influencer networks on song popularity prediction

open access: yesScientific Reports
Forecasting the popularity of new songs has become a standard practice in the music industry and provides a comparative advantage for those that do it well. Considerable efforts were put into machine learning prediction models for that purpose.
Niklas Reisz   +2 more
doaj   +1 more source

Binary Determinantal Complexity

open access: yes, 2015
We prove that for writing the 3 by 3 permanent polynomial as a determinant of a matrix consisting only of zeros, ones, and variables as entries, a 7 by 7 matrix is required.
Hüttenhain, Jesko, Ikenmeyer, Christian
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Complex Mortgages [PDF]

open access: yesSSRN Electronic Journal, 2011
Complex mortgages became a popular borrowing instrument during the bullish housing market of the early 2000s but vanished rapidly during the subsequent downturn. These non-traditional loans (interest only, negative amortization, and teaser mortgages) enable households to postpone loan repayment compared to traditional mortgages and hence relax ...
Gene Amromin   +3 more
openaire   +4 more sources

Infinite Communication Complexity [PDF]

open access: yes, 2014
Suppose that Alice and Bob are given each an infinite string, and they want to decide whether their two strings are in a given relation. How much communication do they need? How can communication be even defined and measured for infinite strings? In this
Guillon, Pierre, Jeandel, Emmanuel
core   +3 more sources

Expansion complexity and linear complexity of sequences over finite fields

open access: yes, 2016
The linear complexity is a measure for the unpredictability of a sequence over a finite field and thus for its suitability in cryptography. In 2012, Diem introduced a new figure of merit for cryptographic sequences called expansion complexity.
Mérai, László   +2 more
core   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Complexity Hierarchies Beyond Elementary

open access: yes, 2016
We introduce a hierarchy of fast-growing complexity classes and show its suitability for completeness statements of many non elementary problems. This hierarchy allows the classification of many decision problems with a non-elementary complexity, which ...
Schmitz, Sylvain
core   +3 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

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