Results 131 to 140 of about 1,601,892 (304)

Complexity and communities: The application of complexity to community studies

, 2015
Understanding community dynamics has always been a challenge for policy-makers. Often community policy has been ineffective and wasteful. This research explores and sets out an alternative, complexity-informed approach to community studies.
Large, David
core  

Spatially embedded dynamics and complexity

, 2010
To gain a deeper understanding of the impact of spatial embedding on the dynamics of complex systems we employ a measure of interaction complexity developed within neuroscience using the tools of statistical information theory. We apply this measure to a
Bullock, Seth, Buckley, Christopher L.
core   +1 more source

International institutions in hard times: how complexity increases resilience

, 2020
This paper asks how institutional complexity affects the resilience of global governance. By drawing on sociological differentiation theory, it interprets growing levels of institutional complexity as a process of institutional differentiation which ...
Faude, Benjamin
core   +1 more source

PROBABILISTIC COST ANALYSIS OF LOGIC PROGRAMS ANÁLISIS DE COSTO PROBABILÍSTICO DE PROGRAMAS LÓGICOS

Ingeniare: Revista Chilena de Ingeniería, 2009
Cost analyses of logic programs have been developed which make it possible to obtain automatically lower and upper bounds of runtime cost of computations.
Héctor Juan Soza Pollman
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

A longitudinal study of functional brain complexity in progressive Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Cross‐sectional resting‐state functional magnetic resonance imaging (rsfMRI) studies have revealed altered complexity with advanced Alzheimer's disease (AD) stages.
Ru Zhang, Leon Aksman, Dilmini Wijesinghe, John M. Ringman, Danny J. J. Wang, Kay Jann, for the Alzheimer's Disease Neuroimaging Initiative   +6 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Searchers' assessments of task complexity for web searching

, 2004
The complexity of search tasks has been shown to be an important factor in searchers' ability to find relevant information and their satisfaction with the performance of search engines.
Bell, David J., David J. Bell, Ruthven, Ian, Ian Ruthven   +3 more
core   +1 more source

Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction. [PDF]

Sci Rep, 2023
Tang SY, Ma HP, Lin C, Lo MT, Lin LY, Chen TY, Wu CK, Chiang JY, Lee JK, Hung CS, Liu LD, Chiu YW, Tsai CH, Lin YT, Peng CK, Lin YH.   +15 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source