Results 151 to 160 of about 1,601,892 (304)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A METHOD TO COMPARE TWO MULTIVARIABLE COMPLEXITY FUNCTIONS [PDF]

open access: yes
The comparison of algorithms complexities can be reduced to the comparison of complexity functions. In two previous papers, we obtained some results related to the comparison of one-variable complexity functions using complexity classes.
Andrei-Horia MOGOS, Adina Magda FLOREA
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A Task Complexity Analysis Method to Study the Emergency Situation under Automated Metro System. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Niu K   +6 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Computability and complexity in analysis

open access: yesJournal of Complexity, 2006
Vasco Brattka   +3 more
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Complexity Era in Economics [PDF]

open access: yes
This article argues that the neoclassical era in economics has ended and is being replaced by a new era. What best characterizes the new era is its acceptance that the economy is complex, and thus that it might be called the complexity era.
David Colander   +2 more
core  

Topological Complexity of Configuration Spaces [PDF]

open access: yes, 2010
In this thesis we study the homotopy invariant TC(X); the topological complexity of a space X. This invariant, introduced by Farber in [15], was originally motivated by a problem in Robotics; the motion planning problem.
COSTA, ARMINDO,EMANUEL   +1 more
core  

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