Results 121 to 130 of about 8,702,509 (349)

A Governance Approach to the Spatial Planning of Atatürk Forest Farm

Ankara Araştırmaları Dergisi
The aim of this study is to discuss how an effective governance process should be established for Atatürk Forest Farm's (AFF) urban policies, spatial planning, and the implementation thereof.
Damla Özdemir, Çiğdem Varol
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Descriptive Complexity Theories

THEORIA, 2008
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openaire   +4 more sources

Phase Change and the Limits of Resilience: A Physics-Inspired Lens on Societal Fragility and Collapse

Recoletos Multidisciplinary Research Journal
Contemporary systemic disruptions in finance, supply chains, ecological regimes, governance and critical infrastructure often appear sudden, yet they usually reflect long periods of hidden stress, declining resilience, and structural weakening beneath ...
Russell John Walker
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mapping the field of complexity theory: A computational approach to understanding changes in the field [PDF]

, 2014
The field of Complexity Theory research has grown considerably over the last two decades, but it is unclear whether the field is, or has ever been, an integrated whole.
Adler, D, Pollack, J, Sankaran, S
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Are We Intentionally Limiting Urban Planning and Intelligence? A Causal Evaluative Review and Methodical Redirection for Intelligence Systems

IEEE Access, 2017
The chronic growth of networked complexities in today's world, now require highly efficient evolvable systems. However, diverse open issues and inabilities are facing urban planning practice and social sciences due to the limitations of artificial ...
Mohamed A. Hawas
doaj   +1 more source

Special Issue “New Frontiers in Parameterized Complexity and Algorithms”: Foreward by the Guest Editors

, 2020
This Special Issue contains eleven articles—surveys and research papers—that represent fresh and ambitious new directions in the area of Parameterized Complexity.
Neeldhara Misra, Meirav Zehavi, Rosamond, Frances, Frances Rosamond, Zehavi, Meirav, Misra, Neeldhara   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source