Results 1 to 10 of about 3,849,337 (390)

Applying the OMOP Common Data Model to Facilitate Benefit-Risk Assessments of Medicinal Products Using Real-World Data from Singapore and South Korea [PDF]

Healthcare Informatics Research, 2022
Objectives The aim of this study was to characterize the benefits of converting Electronic Medical Records (EMRs) to a common data model (CDM) and to assess the potential of CDM-converted data to rapidly generate insights for benefit-risk assessments in ...
Hui Xing Tan, Desmond Chun Hwee Teo, Dongyun Lee, Chungsoo Kim, Jing Wei Neo, Cynthia Sung, Haroun Chahed, Pei San Ang, Doreen Su Yin Tan, Rae Woong Park, Sreemanee Raaj Dorajoo   +10 more
doaj   +1 more source

Phenotyping Diabetes Mellitus on Aggregated Electronic Health Records from Disparate Health Systems

Pharmacoepidemiology, 2023
Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability.
Hui Xing Tan, Rachel Li Ting Lim, Pei San Ang, Belinda Pei Qin Foo, Yen Ling Koon, Jing Wei Neo, Amelia Jing Jing Ng, Siew Har Tan, Desmond Chun Hwee Teo, Mun Yee Tham, Aaron Jun Yi Yap, Nicholas Kai Ming Ng, Celine Wei Ping Loke, Li Fung Peck, Huilin Huang, Sreemanee Raaj Dorajoo   +15 more
doaj   +1 more source

A Rapid Qualitative Screening Method for Isoniazid Tablets Using Handheld NIR Spectrometers in Two Countries

Molecules, 2023
Background: Isoniazid is a leading tuberculosis treating medication. Global supply chains provide essential medicines such as isoniazid to resource-limited areas.
Matthew Eady, Jonelle Caison, Mohammed Jinnah, David Jenkins   +3 more
doaj   +1 more source

Mean kinetic temperature evaluations through simulated temperature excursions and risk assessment with oral dosage usage for health programs

BMC Public Health, 2022
Background Temperature excursions occur during the transport and storage of pharmaceuticals, and often result in considerable losses for public health programs operating in countries with limited resources.
David Jenkins, Aida Cancel, Thomas Layloff   +2 more
doaj   +1 more source

Nationwide safety surveillance of COVID-19 mRNA vaccines following primary series and first booster vaccination in Singapore

Vaccine: X, 2023
Background: The real-world safety profile of COVID-19 mRNA vaccines remains incompletely elucidated. Methods: We performed a nationwide post-market safety surveillance analysis in Singapore, on vacinees aged 5 years and older, through mid-September 2022.
Sreemanee Raaj Dorajoo, Hui Xing Tan, Chun Hwee Desmond Teo, Jing Wei Neo, Yen Ling Koon, Jing Jing Amelia Ng, Mun Yee Tham, Pei Qin Belinda Foo, Li Fung Peck, Pei San Ang, Theen Adena Lim, Wang Woon Jalene Poh, Su Lin Dorothy Toh, Cheng Leng Chan, Ian Douglas, Bee Leng Sally Soh   +15 more
doaj   +1 more source

Adaptation to the Risks of Digitalization: New Survival Trends for States in a Multipolar World

Risks, 2021
The purpose is to study the new survival trends for states in a multipolar world, determine the successfulness of adaptation to the digitalization of different growth poles, and develop the applied recommendations to improve the practice of adaptation to
Julia V. Ragulina, Vladimir F. Ukolov, Oleg V. Shabunevich   +2 more
doaj   +1 more source

The Secrets of a Successful Clinical Trial: Compliance, Compliance, and Compliance [PDF]

Molecular Interventions, 2011
The high failure rate of drugs in clinical trials, especially in the later stages of development, is a significant contributor to the costs and time associated with bringing new molecular entities to market. These costs, estimated to be in excess of $1.5 billion when capitalized over the ten to fifteen years required to develop a new chemical entity ...
Pál, Czobor, Phil, Skolnick
openaire   +2 more sources

Determination of ethanol, isopropyl alcohol and methanol in alcohol-based hand sanitiser to ensure product quality, safety and efficacy

Scientific Reports, 2023
The Coronavirus Disease-2019 (COVID-19) outbreak is an unprecedented global pandemic, sparking grave public health emergencies. One of the measures to reduce COVID-19 transmissions recommended by the World Health Organization is hand hygiene, i.e ...
Nur Dayana Nisbar, Sara Khalida Jamal Khair, Nur Baizura Bujang, Ahmad Yusri Mohd Yusop   +3 more
doaj   +1 more source

Detecting falsified oral contraceptives by visual assessment and diffuse reflectance spectroscopy (350–2500 nm): the need for supplementing traditional pharmacopeia techniques and the public health implications

Heliyon, 2022
Objectives: Substandard and falsified pharmaceuticals can present a major health risk, particularly for low- and middle-income countries. In a Sub-Saharan African market, United States Agency for International Development (USAID) staff found an oral ...
David Jenkins, Cherif Diallo, Michael Payne   +2 more
doaj   +1 more source

Agroeconomic costs for meeting the Environmental Protection Agency's mitigation menu approach to pesticide regulation

Agricultural & Environmental Letters, 2023
In April 2022, the Environmental Protection Agency (EPA) introduced a workplan for pesticide registration and reregistration to meet obligations under the Endangered Species Act (ESA), which included a menu of suggested mitigation measures to reduce ...
Leah M. Duzy, David J. Campana, Richard Brain   +2 more
doaj   +1 more source