Results 41 to 50 of about 1,459,485 (312)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Burnout among Medical Professions during Outbreaks
Journal of the Dow University of Health Sciences, 2021 The COVID-19 outbreak spread globally on March 11, 2020 and WHO declared this disease as a pandemic. This outbreak was sudden and spread all over the world. At the time of writing this article still COVID -19 cases are increasing among several countries.
Salar A. Khan
doaj +1 more source
GV-EXECUTIVO, 2019 Como iniciativas de compliance são bem-sucedidas, muitos não veem necessidade de direcionar ou manter recursos relevantes nesses programas.
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
BMJ, 1998 Editor—Bamforth is correct in spotting the wrong preposition in the quotation from Franz Kafka.1 In the course of some enthusiastic technical editing of my article, Kafka was omitted and restored only as the result of my last minute appeal on the telephone.2 Somehow BT (the telecommunications company), my diction, and the technical editor's hearing ...
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Reforming Indigenous policing: Understanding the context for change
Journal of Community Safety and Well-Being, 2020 Protests over the policing of Black and Indigenous people and people of Colour that started after the death of George Floyd in May 2020 at the hands of the Minneapolis police set the stage for debates about the role of the Canadian police in ensuring ...
Rick Ruddell, John Kiedrowski
doaj +1 more source
Fiscal Year 2006: Compliance & Enforcement Highlights Report
, 2006 This 2nd annual highlights report shows some of the Compliance and Enforcement (C&E) related accomplishments across the NJDEP. It includes summary data on the number of site inspections, investigations, and enforcement actions carried out in the FY 2006
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Frontiers in Medicine, 2018 The objective of this study is to collate and analyse adverse event reports associated with the use of complementary health products (CHP) submitted to the Health Sciences Authority (HSA) of Singapore for the period 2010–2016 to identify various trends ...
Yimin Xu +11 more
doaj +1 more source