Results 61 to 70 of about 1,467,184 (312)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Compliance in 2017 [PDF]

, 2017
War noch vor zehn Jahren das Thema Compliance in weiten Teilen der deutschen Unternehmen unbekannt oder allenfalls aus Presseberichten über aufsehenerregende Skandale einiger Großkonzerne in Fachzirkeln bekannt, so hat sich seitdem viel getan.
Hastenrath, Katharina Britta
core   +2 more sources

A compliance-rendszerek szerepe a vállalati fenntarthatóság és az etikus működés biztosításában

Belügyi Szemle
Cél: A tanulmány célja, hogy feltárja a vállalati compliance-rendszerek szerepét az etikus működés és a fenntarthatóság biztosításában, különös tekintettel a magyar nagyvállalatokra és a nemzetközi „best practice” modellekre.
Zsuzsanna Herman
doaj   +1 more source

Reforming Indigenous policing: Understanding the context for change

Journal of Community Safety and Well-Being, 2020
Protests over the policing of Black and Indigenous people and people of Colour that started after the death of George Floyd in May 2020 at the hands of the Minneapolis police set the stage for debates about the role of the Canadian police in ensuring ...
Rick Ruddell, John Kiedrowski
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Retrospective Study of Reported Adverse Events Due to Complementary Health Products in Singapore From 2010 to 2016

Frontiers in Medicine, 2018
The objective of this study is to collate and analyse adverse event reports associated with the use of complementary health products (CHP) submitted to the Health Sciences Authority (HSA) of Singapore for the period 2010–2016 to identify various trends ...
Yimin Xu, Yimin Xu, Dhavalkumar N. Patel, Suet-Leng P. Ng, Siew-Har Tan, Dorothy Toh, Jalene Poh, Adena Theen Lim, Cheng-Leng Chan, Cheng-Leng Chan, Min-Yong Low, Hwee-Ling Koh   +11 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Real-world insights on nutritional awareness and behaviors among preconception and pregnant women in three Asia Pacific countries

Frontiers in Global Women's Health
IntroductionIn many parts of Asia Pacific (APAC), insufficient intake of micronutrients that are important for conception and pregnancy remains a prevalent issue among women of reproductive age.
Denise Furness, Nguyen Khanh Trang Huynh, Ligaya Kaufmann, Jue Liu, Thi Bich Ngoc Nguyen, Ella Schaefer, Lucy Tan, Ching Danica Yau, Qi Yu   +8 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Interagency Compliance Network's ... report to the Oregon Legislature [PDF]

This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Oregon Interagency Compliance Network participating agencies:

core