Results 51 to 60 of about 3,290,407 (310)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Towards Data Protection Compliance [PDF]
, 2010 Privacy and data protection are fundamental issues nowadays for every organization. This paper calls for the development of methods, techniques and infrastructure to allow the deployment of privacy-aware IT systems, in which humans are integral part of ...
Etalle, Sandro +2 more
core +2 more sources
Reducing hospital associated infection : a role for social marketing [PDF]
, 2013 Purpose: Although hand hygiene is seen as the most important method to prevent the transmission of hospital associated infection in the UK, hand hygiene compliance rates appear to remain poor.
Conway, A, Langley, S
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Reforming Indigenous policing: Understanding the context for change
Journal of Community Safety and Well-Being, 2020 Protests over the policing of Black and Indigenous people and people of Colour that started after the death of George Floyd in May 2020 at the hands of the Minneapolis police set the stage for debates about the role of the Canadian police in ensuring ...
Rick Ruddell, John Kiedrowski
doaj +1 more source
Monitoring Compliance with Open Access policies [PDF]
, 2015 In the last few years, academic communities have seen an increase in the number of Open Access (OA) policies being adopted at the institutional and funder levels.
[contributor] McCutcheon, Valerie +2 more
core
Environmental (waste) compliance control systems for UK SMEs
, 2015 While the ‘environment’ is often perceived as a heavily regulated area of business, in reality, directly-regulated businesses represent a small proportion of the business community.
Kemp, Simon +2 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in Medicine, 2018 The objective of this study is to collate and analyse adverse event reports associated with the use of complementary health products (CHP) submitted to the Health Sciences Authority (HSA) of Singapore for the period 2010–2016 to identify various trends ...
Yimin Xu +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source