Results 51 to 60 of about 1,467,184 (312)
Revista Justicia y Derecho, 2020 En el presente trabajo se pretende abordar cómo el feminismo ha influido en el Derecho Penal chileno, observando en primer lugar el fenómeno político del feminismo, considerando la gran fuerza que este movimiento ha tenido en Chile, para luego, en ...
Luis Hernán Acevedo Espínola
doaj +1 more source
The promise of automated compliance checking
Developments in the Built Environment, 2021 The quest to automate compliance checking processes needed for planning, design, construction and operations has been an active research topic for half a century.
Robert Amor, Johannes Dimyadi
doaj +1 more source
BMJ, 1998 Editor—Bamforth is correct in spotting the wrong preposition in the quotation from Franz Kafka.1 In the course of some enthusiastic technical editing of my article, Kafka was omitted and restored only as the result of my last minute appeal on the telephone.2 Somehow BT (the telecommunications company), my diction, and the technical editor's hearing ...
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Il regime di adempimento collaborativo inteso come traduzione di tax compliance in Italia [PDF]
, 2015 Alla base di una corretta tax compliance è necessario sottolineare che vi sono elementi di natura differente quali, ad esempio, concetti di deterrenza, di norme, di equità e di fiducia e non solo.
STRIANESE, loredana
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Studie : die Rendite von Compliance [PDF]
, 2020 Wie weise ich meine Compliance-Erfolge nach? Das untersuchten Forscher der Schweizer Hochschule ZHAW (Zurich University) in einer Studie.
Diem, Maximilian, Hastenrath, Katharina
core +2 more sources
Разработка и регистрация лекарственных средствIntroduction. Sorafenib is an antineoplastic drug belonging to class IIc according to the biopharmaceutical classification system (BCS) due to the presence of both acidic and basic properties.
A. V. Suvorova +6 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source