Results 81 to 90 of about 4,177,944 (282)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Use of compliant mechanisms in gearbox applications

, 2020
The purpose of this thesis is to prove that the use of compliant mechanisms in gearbox applications is viable. Compliant mechanisms are developed for their implementation in Scania’s hybrid asynchronous gearboxes.
Manresa Pérez, Álvaro, Gonzalez Sanchez, Ander   +1 more
core   +2 more sources

SOFTWARE FOR SYNTHESIS OF COMPLIANT MECHANISMS WITHOUT INTERSECTING ELEMENTS

Facta Universitatis. Series: Mechanical Engineering, 2014
A compliant mechanism is defined as a single piece structure that transfer motion or force through elastic deformation. The synthesis of this kind of mechanisms represents a challenging task, especially because their flexible segments usually must ...
Andrija P. Milojević, Nenad D. Pavlović   +1 more
doaj  

Alzheimer's Disease Biomarkers Measured by Capillary Blood Collection Versus Venous Plasma and Cerebrospinal Fluid

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho, Ziling Shen, Alexandria Lewis, Megha Patel, Anny Zheng, Gianna Proscino, Thaovy Ho, Jiangxia Wang, Marilyn Albert, Abhay Moghekar   +9 more
wiley   +1 more source

Design of Compliant Mechanisms: Applications to MEMS [PDF]

, 2001
Compliant mechanisms are single-piece flexible structures that deliver the desired motion by undergoing elastic deformation as opposed to jointed rigid body motions of conventional mechanisms. Compliance in design leads to jointless, no-assembly (Fig. 1),
Kota, Sridhar, Joo, Jinyong, Li, Zhe, Rodgers, Steven M., Sniegowski, Jeff, Jeff Sniegowski, Sridhar Kota, Zhe Li, Steven M. Rodgers, Jinyong Joo   +9 more
core   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Fabrication Methods of Compliant Mechanisms

Procedia Engineering, 2017
Abstract This paper will present specific procedures and processing methods of compliant mechanisms. Will mention a few unconventional and conventional processing methods for compliant mechanisms. Also, will present, detailed, three obtaining methods of these mechanisms, authors participating at production process, such as: milling method, 3D ...
Daniel Lateş, Marius Căşvean, Sorina Moica   +2 more
openaire   +1 more source

Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch, Hannah Schwartz, Kimberly H. Markowitz, Abhishek Jaywant, Christopher D. Hildenbrand, Jai Perumal, Ulrike W. Kaunzner, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

METHODOLOGY FOR COMPLIANT MECHANISMS DESIGN

, 1986
The purpose of this research program is to develop a design methodology for compliant mechanisms. Compliant mechanisms represent a class of mechanical systems which makes use of large-displacement flexible elements in design, as opposed to the use of ...
HER, INNCHYN
core   +1 more source