Results 111 to 120 of about 7,641,023 (289)

Strategy exploration for developing robust lyophilized cell-free systems

open access: yesBiotechnology Notes
Cell-free protein synthesis system is emerging as a powerful tool for rapid expression of therapeutic proteins. However, one drawback of cell-free technology is the necessity to store the major components below freezing in bulky aqueous solutions.
Junzhu Yang   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Coupling Neumann development and component mode synthesis methods for stochastic analysis of random structures

open access: yesJournal of Materials and Engineering Structures, 2014
In this paper, we propose a method to calculate the first two moments (mean and variance) of the structural dynamics response of a structure with uncertain variables and subjected to random excitation.
Driss Sarsri
doaj  

A Comparison of Component Mode Synthesis Methods for Cyclic Structures

open access: yes, 2000
International audienceSeveral component mode synthesis methods with fixed, free and hybrid interface are used to compute the eigen solutions and the frequency response of a cyclic structure in combination with the cyclic symmetry properties.
Tran, Duc-Minh
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Multi Sensor Image Fusion using Empirical Mode Decomposition [PDF]

open access: yes, 2013
Image fusion is a process of combining relevant information from two or more images from different sensors based on certain algorithm. Many algorithms have been proposed for pixel level image fusion.
Naidu, VPS, Shakthipriya, VS
core  

Numerical Instability of Classical Free-Interface Component Mode Synthesis Techniques

open access: yes, 2003
International audienceFinite element based component mode synthesis (CMS) techniques are popular tools used in structural dynamics applications.In CMS, the original structure is subdivided into smaller substructures, or components, for which normal modes
Bladh, Ronnie   +2 more
core   +1 more source

Dynamic substructuring for shock spectrum analysis using component mode synthesis [PDF]

open access: yes, 1988
Component mode synthesis was used to analyze different types of structures with MSC NASTRAN. The theory and technique of using Multipoint Constraint Equations (MPCs) to connect substructures to each other or to a common foundation is presented ...
Bogert, Philip B.   +3 more
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

The metabolic underpinnings of sebaceous lipogenesis

open access: yesCommunications Biology
Sebaceous glands synthesize and secrete sebum, a mélange of lipids and other cellular products that safeguards the mammalian integument. Differentiating sebocytes delaminate from the basal membrane and dislodge towards the gland’s middle, where they ...
Maria Schmidt   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy