Results 171 to 180 of about 420,621 (305)

VASELFCARE – Componentes gráficas

open access: yes, 2019
A tecnologia tem vindo a evoluir a passos largos, trazendo bastantes benefícios para a Humanidade, sento esta actualmente aplicada em diversos âmbitos do dia a dia, como a educação, a saúde, a gestão, entre outros. A utilização desta vertente na área da saúde, mais particularmente nos cuidados de saúde, torna-se uma mais valia para a prevenção e ...
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Análisis de Componentes Principales

open access: yes, 2009
Análisis de Componentes Principales: transformación de un vector aleatorio en otro con componentes incorreladashttps://laboratoriosvirtuales.upv.es/eslabon/pcaIgual García, J. (2009). Análisis de Componentes Principales.
Igual García, Jorge
core  

La Península Ibérica en la Planificación Militar Aliada

open access: yesRevista UNISCI, 2014
Antonio Marquina
doaj  

[Controversies in primary care: Use of beta-blockers after acute myocardial infarction]. [PDF]

open access: yesAten Primaria
Fransi Galiana L   +2 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy