Results 41 to 50 of about 5,261 (264)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Evolución temporal y diversificación en Artemisia y géneros relacionados (Anthemideae, Asteraceae)

Collectanea Botanica, 2011
Evolución temporal y diversificación en Artemisia y géneros relacionados (Anthemideae, Asteraceae).- Con el objetivo de estimar el tiempo de diversificación de los linajes de la subtribu Artemisiinae y el grupo Artemisia se aplicó un análisis de ...
M. Sanz, G. M. Schneeweiss, R. Vilatersana, j. Vallès   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The complete chloroplast genome of Opisthopappus taihangensis (Ling) Shih

Mitochondrial DNA. Part B. Resources, 2019
Opisthopappus taihangensis (Ling) Shih is a monotypic species (Anthemideae, Asteraceae) and an endemic endangered plant of China. In this study, we sequenced the complete chloroplast genome of O. taihangensis using Illumina HiSeq X Ten platform.
Junyu Gu, Zhen Wei, Caipeng Yue, Xuemin Xu, Tao Zhang, Qingfei Zhao, Shuoming Fu, Dengxu Yang, Shixin Zhu   +8 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Phylogenetic implications and characterization of the chloroplast genome of Atractylodes macrocephala (Compositae), an herb species to China

Mitochondrial DNA. Part B. Resources, 2023
The rhizome of Atractylodes macrocephala is one of the most commonly used herbs in China. In this paper, we presented the complete chloroplast genome of A. macrocephala. The chloroplast genome of A.
Bin Zhu, Tianyi Cao, Yuying Lang, Jun Fei   +3 more
doaj   +1 more source

A Target Enrichment Method for Gathering Phylogenetic Information from Hundreds of Loci: An Example from the Compositae

Applications in Plant Sciences, 2014
Premise of the study: The Compositae (Asteraceae) are a large and diverse family of plants, and the most comprehensive phylogeny to date is a meta-tree based on 10 chloroplast loci that has several major unresolved nodes.
Jennifer R. Mandel, Rebecca B. Dikow, Vicki A. Funk, Rishi R. Masalia, S. Evan Staton, Alex Kozik, Richard W. Michelmore, Loren H. Rieseberg, John M. Burke   +8 more
doaj   +1 more source

Characterization and phylogenetic analysis of the complete chloroplast genome of Cyanthillium cinereum (L.) H. Rob

Mitochondrial DNA. Part B. Resources, 2022
Cyanthillium cinereum is a member of the tribe Vernonieae from the family Compositae. The tribe was traditionally placed in the subfamily Cichorioideae, but is recently proposed to be placed in its own subfamily Vernonioideae.
Tin-Yan Siu, Kwan-Ho Wong, Bobby Lim-Ho Kong, Hoi-Yan Wu, Grace Wing-Chiu But, Pang-Chui Shaw, David Tai-Wai Lau   +6 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source