Results 151 to 160 of about 1,534,395 (319)
Armoring Boron Nitride with Pyrolytic Carbon Layers for Tunable Rigidity and Flexibility
Advanced ScienceCeramic aerogels are acclaimed as ideal materials for extreme environments due to their ultrahigh porosity, low density, and exceptional thermal stability.
Meng Lan +5 more
doaj +1 more source
, 2010 Traditionally high strain rate material characterisations have been conducted using strain gauges and/or cross head displacements in servo-hydraulic test machines, and force transducers in split Hopkinson bar experiments.
Syngellakis, Stavros +8 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Grouping similar fibre types in hybrid discontinuous composite materials
, 2017 A virtual testing framework and a new manufacturing process were developed to investigate how grouping similar fibre types within a hybrid discontinuous composite affects the strength and pseudo-ductility of the material.
Yu H. +4 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Effect of Production Parameters on the Properties of Composite Wires
, 2006 Nowadays, metal matrix composites have many new areas of application owing to their excellent properties - for example their great tensile strength and high Young’s modulus with its relatively low weight.
Dobránszky, János +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source